Painsi Clemens, Hirtenfelder Alexander, Lange-Asschenfeldt Bernhard, Quehenberger Franz, Wolf Peter
Department of Dermatology, Medical University of Graz, Graz, Austria.
Skin Pharmacol Physiol. 2017;30(6):324-328. doi: 10.1159/000481544. Epub 2017 Nov 2.
Periodontitis and psoriasis are suggested to be co-occurring, chronic inflammatory conditions with overlapping characteristics. However, respective evidence is rare and data on risk factors of periodontitis in psoriasis patients are minimal. The aim of this study was to expand the evidence of psoriasis-associated periodontitis and establish a potential risk profile for periodontitis. In total, data from 209 exacerbated psoriasis patients were retrospectively analyzed on recordings of periodontitis and compared with those of 91 patients with chronic spontaneous urticaria (CSU). Analysis showed a significantly increased prevalence of periodontitis in psoriasis compared to CSU patients with an odds ratio of 3.76 (95% CI = 1.60-10.27, p = 0.001). Within the psoriatic subtypes, the presence of the inverse type (affecting intertriginous body areas) was strongly linked to periodontitis with an odds ratio of 5.11 (95% CI = 1.36-20.38, p = 0.006). These results are enlarging the evidence for psoriasis-associated periodontitis and identify a link between the inverse type of psoriasis and periodontitis.
牙周炎和银屑病被认为是同时发生的慢性炎症性疾病，具有重叠特征。然而，相关证据很少，关于银屑病患者牙周炎危险因素的数据也极少。本研究的目的是扩大与银屑病相关的牙周炎的证据，并建立牙周炎的潜在风险概况。总共对209例病情加重的银屑病患者的牙周炎记录进行了回顾性分析，并与91例慢性自发性荨麻疹（CSU）患者的记录进行了比较。分析表明，与CSU患者相比，银屑病患者牙周炎的患病率显著增加，优势比为3.76（95%CI = 1.60 - 10.27，p = 0.001）。在银屑病亚型中，反向型（累及屈侧身体部位）的存在与牙周炎密切相关，优势比为5.11（95%CI = 1.36 - 20.38，p = 0.006）。这些结果扩大了与银屑病相关的牙周炎的证据，并确定了反向型银屑病与牙周炎之间的联系。
