Bragg Dee Ann, Crowl Ashley, Manlove Emily
Via Christi Family Medicine Residency, University of Kansas School of Medicine (KUSM)-Wichita, 1121 South Clifton Street, Wichita, KS 67218, USA.
University of Kansas School of Pharmacy, 1121 South Clifton Street, Wichita, KS 67218, USA.
Prim Care. 2017 Dec;44(4):631-642. doi: 10.1016/j.pop.2017.07.006. Epub 2017 Oct 5.
More than 2 million Americans are infected with hepatitis C virus (HCV), and only about half are aware that they are infected. Primarily blood-borne, risk factors for the virus include injection or intranasal drug use, unregulated tattoos, incarceration, and blood transfusion before 1992. In addition, 75% of those with the virus were born between 1945 and 1965, thus making the baby-boomer cohort a population of screening interest. Because acute and early chronic HCV are often asymptomatic, screening of at-risk individuals is of utmost importance. Left untreated, HCV can go on to produce significant hepatic and extrahepatic manifestations.
超过200万美国人感染了丙型肝炎病毒（HCV），而只有约一半的人意识到自己已被感染。该病毒主要通过血液传播，其风险因素包括注射或鼻内使用毒品、不规范纹身、监禁以及1992年前的输血。此外，75%的病毒感染者出生于1945年至1965年之间，因此婴儿潮一代成为筛查的重点人群。由于急性和早期慢性HCV感染通常没有症状，对高危个体进行筛查至关重要。若不加以治疗，HCV会进而引发严重的肝脏和肝外表现。
