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黑素毛母细胞瘤:一种罕见的色素性毛母细胞瘤变异型。

Melanotrichoblastoma: a rare pigmented variant of trichoblastoma.

作者信息

Quist Erin E, DiMaio Dominick J

机构信息

Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, USA.

出版信息

Cutis. 2017 Oct;100(4):243-246.

PMID:29136051
Abstract

Trichoblastomas are rare cutaneous tumors arising from the hair bulb and mesenchyme. Although they are benign, they can pose a diagnostic dilemma for the clinician and pathologist because they clinically and histologically mimic more common lesions such as basal cell carcinomas (BCCs) and trichoepitheliomas. It is important for the clinician and pathologist to be aware of such tumors and their variants. We present a case of a melanotrichoblastoma, an exceedingly rare variant of trichoblastoma, as well as review the current literature on the clinical presentation and histologic differentiation of these unique tumors with their more commonly seen mimics.

摘要

毛母细胞瘤是一种起源于毛球和间充质的罕见皮肤肿瘤。尽管它们是良性的,但它们可能给临床医生和病理学家带来诊断难题,因为它们在临床和组织学上与更常见的病变如基底细胞癌(BCC)和毛发上皮瘤相似。临床医生和病理学家了解此类肿瘤及其变体很重要。我们报告一例黑素毛母细胞瘤,这是毛母细胞瘤一种极其罕见的变体,并回顾了关于这些独特肿瘤及其更常见的相似病变的临床表现和组织学鉴别诊断的当前文献。

相似文献

1
Melanotrichoblastoma: a rare pigmented variant of trichoblastoma.黑素毛母细胞瘤:一种罕见的色素性毛母细胞瘤变异型。
Cutis. 2017 Oct;100(4):243-246.
2
Differential diagnosis of basal cell carcinoma and benign tumors of cutaneous appendages originating from hair follicles by using CD34.利用CD34对基底细胞癌和起源于毛囊的皮肤附属器良性肿瘤进行鉴别诊断。
Asian Pac J Cancer Prev. 2010;11(6):1615-9.
3
Melanotrichoblastoma: immunohistochemical study of a variant of pigmented trichoblastoma.黑素毛母细胞瘤:色素性毛母细胞瘤一种变体的免疫组织化学研究
Am J Dermatopathol. 2002 Dec;24(6):498-501. doi: 10.1097/00000372-200212000-00008.
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Giant melanotrichoblastoma.巨大黑素毛发母细胞瘤
Am J Dermatopathol. 2011 May;33(3):e37-40. doi: 10.1097/DAD.0b013e3181dfd120.
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Trichogenic trichoblastoma. An unusual neoplasm of hair germ.毛发源性毛母细胞瘤。一种不寻常的毛胚肿瘤。
Am J Dermatopathol. 1990 Apr;12(2):175-81.
6
Benign follicular tumors.良性滤泡性肿瘤
An Bras Dermatol. 2015 Nov-Dec;90(6):780-96; quiz 797-8. doi: 10.1590/abd1806-4841.20154114.
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Trichoblastoma with sebaceous and sweat gland differentiation.具有皮脂腺和汗腺分化的毛发母细胞瘤。
Br J Dermatol. 2001 May;144(5):1090-2. doi: 10.1046/j.1365-2133.2001.04209.x.
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Trichoblastoma trichoepiteliomatosum of the scalp.头皮毛发母质瘤样毛发上皮瘤
Plast Reconstr Surg. 2003 Nov;112(6):1745-6. doi: 10.1097/01.PRS.0000084576.71826.7E.
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Trichogerminoma.毛发胚细胞瘤
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Trichofolliculoma of the upper lip: report of a case.上唇毛发上皮瘤:1例报告
Int J Oral Maxillofac Surg. 1999 Apr;28(2):135-6.

引用本文的文献

1
Melanotrichoblastoma: A Histopathological Case Report of a Rare Pigmented Variant of Trichoblastoma.黑素毛母细胞瘤:一例罕见色素沉着型毛母细胞瘤的组织病理学病例报告
Reports (MDPI). 2025 Aug 1;8(3):130. doi: 10.3390/reports8030130.
2
Melanotrichoblastoma Arising on Nevus Sebaceous: A Rare Occurence.皮脂腺痣上发生的黑素毛母细胞瘤:一种罕见病例。
Indian J Dermatol. 2025 Mar-Apr;70(2):105-106. doi: 10.4103/ijd.ijd_1197_23. Epub 2025 Feb 27.
3
Two Cases of Pigmented Basal Cell Carcinoma in African American Patients.两例非裔美国患者的色素性基底细胞癌
Cureus. 2024 Jun 21;16(6):e62862. doi: 10.7759/cureus.62862. eCollection 2024 Jun.
4
Melanotrichoblastoma: sixth case report in the literature.黑素毛母细胞瘤:文献中的第六例报告。
An Bras Dermatol. 2023 Nov-Dec;98(6):871-874. doi: 10.1016/j.abd.2022.07.011. Epub 2023 Jun 29.
5
The Multiple Faces of Nodular Trichoblastoma: Review of the Literature with Case Presentation.结节性毛发母细胞瘤的多面性:文献综述及病例报告
Dermatopathology (Basel). 2021 Jul 5;8(3):265-270. doi: 10.3390/dermatopathology8030032.
6
Trichoblastoma Arising From the Nevus Sebaceus of Jadassohn.起源于 Jadassohn 皮脂腺痣的毛发母细胞瘤
Cureus. 2021 May 29;13(5):e15325. doi: 10.7759/cureus.15325. eCollection 2021 May.