Gupta Veena, Bhutani Namita, Marwah Nisha, Sen Rajeev
Deptt. of Pathology, PGIMS, Rohtak, Haryana, India.
Int J Surg Case Rep. 2017;41:327-331. doi: 10.1016/j.ijscr.2017.10.060. Epub 2017 Nov 10.
Cutaneous metastasis from primary visceral malignancy is a relatively uncommon clinical entity, with a reported incidence of 0.22%-10% among various series. However, the presence of cutaneous metastasis as the first sign of a clinically silent visceral cancer is exceedingly rare.
We describe here a case of an asymptomatic male patient who presented with a solitary scalp metastasis as the initial manifestation of an underlying lung cancer. Diagnostic evaluation revealed advanced disease.
The report emphasizes that physicians should be aware of this rare clinical entity, and appropriate investigation should be arranged for early diagnosis and initiation of the appropriate treatment. The occurrence of skin lesions in lung cancer announces an ominous prognosis.
We conclude that the possibility of metastatic skin disease should always be considered in the differential diagnosis in patients with a history of smoking or lung cancer presenting with cutaneous nodules.
原发性内脏恶性肿瘤的皮肤转移是一种相对罕见的临床情况,在不同系列报道中的发生率为0.22% - 10%。然而,皮肤转移作为临床隐匿性内脏癌的首发症状极为罕见。
我们在此描述一例无症状男性患者,其以孤立性头皮转移作为潜在肺癌的初始表现。诊断评估显示疾病已进展。
该报告强调医生应知晓这种罕见的临床情况,并应安排适当的检查以进行早期诊断并启动适当的治疗。肺癌出现皮肤病变预示预后不良。
我们得出结论,对于有吸烟史或患有肺癌且出现皮肤结节的患者,在鉴别诊断时应始终考虑转移性皮肤病的可能性。