MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Complex Tissue Regeneration, Maastricht University, Maastricht, The Netherlands.
Department of Metallurgical, Materials and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX, USA.
Trends Biotechnol. 2018 Apr;36(4):384-402. doi: 10.1016/j.tibtech.2017.10.015. Epub 2017 Nov 11.
Biofabrication holds the potential to generate constructs that more closely recapitulate the complexity and heterogeneity of tissues and organs than do currently available regenerative medicine therapies. Such constructs can be applied for tissue regeneration or as in vitro 3D models. Biofabrication is maturing and growing, and scientists with different backgrounds are joining this field, underscoring the need for unity regarding the use of terminology. We therefore believe that there is a compelling need to clarify the relationship between the different concepts, technologies, and descriptions of biofabrication that are often used interchangeably or inconsistently in the current literature. Our objective is to provide a guide to the terminology for different technologies in the field which may serve as a reference for the biofabrication community.
生物制造有可能制造出比现有再生医学疗法更能重现组织和器官复杂性和异质性的构建体。这些构建体可用于组织再生或作为体外 3D 模型。生物制造正在成熟和发展，具有不同背景的科学家正在加入这个领域，这凸显了在术语使用方面需要统一。因此，我们认为迫切需要澄清当前文献中经常互换或不一致使用的生物制造的不同概念、技术和描述之间的关系。我们的目标是为该领域的不同技术提供术语指南，该指南可以作为生物制造界的参考。
