CNRS, Laboratoire de Biogenèse Membranaire, UMR5200, Bordeaux, France.
Université de Bordeaux, Laboratoire de Biogenèse Membranaire, UMR5200, Bordeaux, France.
J Exp Bot. 2018 Mar 14;69(6):1287-1299. doi: 10.1093/jxb/erx392.
Autophagy is a critical pathway for plant adaptation to stress. Macroautophagy relies on the biogenesis of a specialized membrane named the phagophore that maturates into a double membrane vesicle. Proteins and lipids act synergistically to promote membrane structure and functions, yet research on autophagy has mostly focused on autophagy-related proteins while knowledge of supporting lipids in the formation of autophagic membranes remains scarce. This review expands on studies in plants with examples from other organisms to present and discuss our current understanding of lipids in membrane dynamics associated with the autophagy pathway in plants.
自噬是植物适应胁迫的关键途径。巨自噬依赖于一种特殊膜的生物发生,这种膜被称为吞噬体,它成熟为双层膜泡。蛋白质和脂质协同作用促进膜结构和功能,但自噬研究主要集中在自噬相关蛋白上,而对形成自噬膜的支持脂质的知识仍然很少。本综述通过来自其他生物体的例子扩展了对植物的研究,提出并讨论了我们目前对与植物自噬途径相关的膜动态中的脂质的理解。