Samoĭlov M O, Sofronov G A, Alekseev M G
Biull Eksp Biol Med. 1989 Jan;107(1):50-1.
Using the complex methodical approach on the basis of in vivo microscopy and chlortetracycline fluorescent probe of the cat brain cortex preparation the authors studied the changes in the content of the bound calcium in the structures of II-III motor cortex layers in response to influence by metrasol. Correlation between rapid decrease of some part of the bound calcium and development of neuron seizures was discovered. Moreover process of calcium absorption by intracellular membranes in response to influence of metrasol in high doses was revealed. Apparently functional different intracellular membranes are involved in this process.
作者采用基于体内显微镜检查和猫脑皮质制剂金霉素荧光探针的复杂方法，研究了在美特拉索作用下，II-III运动皮质层结构中结合钙含量的变化。发现结合钙的某些部分快速减少与神经元癫痫发作的发展之间存在相关性。此外，还揭示了在高剂量美特拉索作用下，细胞内膜对钙的吸收过程。显然，功能不同的细胞内膜参与了这一过程。
