Jilani Kausar, Zulfiqar Bushra, Memon Qadir Bux, Fahim Muhammad Faisal
Dr. Kausar Jilani, MCPS, FCPS. Department of Gynecology & Obstetrics Unit-II, Al-Tibri Medical College & Hospital, Isra University, Karachi, Pakistan.
Dr. Bushra Zulfiqar, MCPS, FCPS. Department of Gynecology & Obstetrics Unit-II, Al-Tibri Medical College & Hospital, Isra University, Karachi, Pakistan.
Pak J Med Sci. 2017 Sep-Oct;33(5):1265-1268. doi: 10.12669/pjms.335.12493.
To determine the frequency and the risk factors of hepatitis C virus in pregnant women at Al-Tibri Medical College & Hospital in Gadap Town Karachi.
This was a descriptive cross sectional study conducted at Obstetrics & Gynecology OPD of Al-Tibri Medical College & Hospital, Isra University Karachi Campus from 10 June to 10 September 2016. A total of 400 pregnant women of 16-45 years of age, who came in outpatient department for antenatal checkup were selected for the study. The diagnosed cases of Hepatitis C were excluded from the study. Detailed history including age, parity, risk factor like history of transfusion, previous surgeries, vaginal deliveries was taken and relevant examination was performed. Patients on routine antenatal investigation if found to have Anti HCV positive on Immunochromatography Test (ICT) method were further confirmed by Elisa. A well designed proforma was used for data collection.
During the period of 3 months 400 women in antenatal clinic were tested for hepatitis C, out of which 27 (6.6%) were positive for HCV antibodies. The age of the women included ranges from 16-45 years. Thirteen (7.9%) pregnant women having HCV +ve antibodies fell in 26-30 years of age group. From 27 HCV +ve patients, 19 (70.3%) were multigravida & 8 (29.6%) were primigravida. Majority of the patients (77%) had history of injections.
There is high prevalence of Hepatitis C infection among pregnant female in our setup. The possible risk factors are injection, blood transfusion and surgery.
确定卡拉奇加达普镇阿尔 - 提卜里医学院及医院孕妇中丙型肝炎病毒的感染率及危险因素。
这是一项描述性横断面研究，于2016年6月10日至9月10日在卡拉奇伊斯玛仪大学阿尔 - 提卜里医学院及医院妇产科门诊进行。共选取400名年龄在16 - 45岁、前来门诊进行产前检查的孕妇作为研究对象。已确诊的丙型肝炎病例被排除在研究之外。记录详细病史，包括年龄、产次、输血史、既往手术史、阴道分娩史等危险因素，并进行相关检查。对进行常规产前检查的患者，若免疫层析试验（ICT）检测抗HCV呈阳性，则进一步通过酶联免疫吸附测定（ELISA）进行确认。使用精心设计的表格进行数据收集。
在3个月的时间里，对400名产前门诊妇女进行了丙型肝炎检测，其中27名（6.6%）HCV抗体呈阳性。这些妇女的年龄在16 - 45岁之间。13名（7.9%）HCV抗体呈阳性的孕妇年龄在26 - 30岁组。在27名HCV阳性患者中，19名（70.3%）为经产妇，8名（29.6%）为初产妇。大多数患者（77%）有注射史。
在我们的研究环境中，孕妇中丙型肝炎感染率较高。可能的危险因素是注射、输血和手术。
