Wen Xu-Dong, Wang Tao, Huang Zhu, Zhang Hong-Jian, Zhang Bing-Yin, Tang Li-Jun, Liu Wei-Hui
General Surgery Center, Chengdu Military General Hospital, Chengdu, Sichuan Province, China.
Department of General Surgery, The 515th Hospital of PLA, Wuxi, Jiangsu Province, China.
Therap Adv Gastroenterol. 2017 Nov;10(11):853-864. doi: 10.1177/1756283X17731489. Epub 2017 Sep 21.
Hepatolithiasis is the presence of calculi within the intrahepatic bile duct specifically located proximal to the confluence of the left and right hepatic ducts. The ultimate goal of hepatolithiasis treatment is the complete removal of the stone, the correction of the associated strictures and the prevention of recurrent cholangitis. Although hepatectomy could effectively achieve the above goals, it can be restricted by the risk of insufficient residual liver volume, and has a 15.6% rate of residual hepatolithiasis. With improvements in minimally invasive surgery, post-operative cholangioscopy (POC), provides an additional option for hepatolithiasis treatment with higher clearance rate and fewer severe complications. POC is very safe, and can be performed repeatedly until full patient benefit is achieved. During POC three main steps are accomplished: first, the analysis of the residual hepatolithiasis distribution indirectly by imaging methods or directly endoscopic observation; second, the establishment of the surgical pathway to relieve the strictures; and third, the removal of the stone by a combination of different techniques such as simple basket extraction, mechanical fragmentation, electrohydraulic lithotripsy or laser lithotripsy, among others. In summary, a step-by-step strategy of POC should be put forward to standardize the procedures, especially when dealing with complicated residual hepatolithiasis. This review briefly summarizes the classification, management and complications of hepatolithiasis during the POC process.
肝内胆管结石是指肝内胆管内存在结石,具体位于左右肝管汇合处近端。肝内胆管结石治疗的最终目标是完全清除结石、纠正相关狭窄并预防复发性胆管炎。虽然肝切除术可以有效实现上述目标,但可能会受到残余肝体积不足风险的限制,并且存在15.6%的残余肝内胆管结石发生率。随着微创手术的进步,术后胆管镜检查(POC)为肝内胆管结石治疗提供了另一种选择,其清除率更高,严重并发症更少。POC非常安全,可以反复进行,直到患者充分受益。在POC过程中,主要完成三个步骤:首先,通过影像学方法间接或直接内镜观察分析残余肝内胆管结石的分布;其次,建立解除狭窄的手术通路;第三,通过简单篮式取石、机械碎石、液电碎石或激光碎石等不同技术组合去除结石。总之,应提出POC的分步策略以规范操作程序,尤其是在处理复杂的残余肝内胆管结石时。本综述简要总结了POC过程中肝内胆管结石的分类、处理及并发症。