Jeswani Sunil, Drazin Doniel, Shirzadi Ali, Fan Xuemo, Johnson J Patrick
Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles,CA USA.
Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA USA.
World J Oncol. 2011 Dec;2(6):314-318. doi: 10.4021/wjon413w. Epub 2011 Dec 19.
Endometriosis consists of ectopic endometrial tissue outside of the uterine cavity. It is typically benign. It may cause neurological symptoms if involving the central or peripheral nervous system. We present in this report a 46-year-old Caucasian female with progressively worsening lumbar pain with radiation to her left anterior thigh. MR imaging showed an enhancing mass in the L4 neural foramen, intrepreted as a nerve sheath tumor. At operation the nerve showed extrinsic and intrinsic abnormality, proven to be endometriosis. Postoperatively, the patient reported relief from her radiculopathy. We review the previous cases, discuss the pathogenesis and additional characteristics that highlight intraspinal endometriosis, although rare, should be considered as a potential cause of neurologic symptoms in women. Surgical resection is recommended in cases having severe or worsening neurologic symptoms or signs of cauda equina syndrome. Adjunctive treatment may be used in cases of residual or recurrent lesions.
子宫内膜异位症是指子宫腔外存在异位的子宫内膜组织。它通常为良性。如果累及中枢或周围神经系统,可能会引起神经症状。在本报告中,我们介绍了一名46岁的白种女性,她的腰痛逐渐加重,并向左前大腿放射。磁共振成像显示L4神经孔有一个强化肿块,被诊断为神经鞘瘤。手术中发现神经存在外在和内在异常,经证实为子宫内膜异位症。术后,患者报告神经根病症状缓解。我们回顾了既往病例,讨论了发病机制以及突出椎管内子宫内膜异位症的其他特征,尽管这种情况罕见,但应被视为女性神经症状的潜在原因。对于出现严重或进行性神经症状或马尾综合征体征的病例,建议进行手术切除。对于残留或复发病变的病例,可采用辅助治疗。