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为贫困及医疗服务不足人群进行肺癌筛查:是否应进行常规筛查?

Lung Cancer Screening for the Poor and Underserved: Should Routine Screening be Performed?

作者信息

Verma Vaibhav, Gotlieb Vladimir K, Fogel Joshua, Multz Alan S, Sharma Geeti

机构信息

Nassau University Medical Center affiliated with North Shore/Long Island Jewish Health Care System. Department of Medicine, Division of Hematology and Oncology, 2201 Hempstead Turnpike, East Meadow, NY 11554, USA.

Department of Finance and Business Management, Brooklyn College, Brooklyn, New York, USA.

出版信息

World J Oncol. 2012 Jun;3(3):97-102. doi: 10.4021/wjon509w. Epub 2012 Jul 5.

DOI:10.4021/wjon509w
PMID:29147289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5649787/
Abstract

BACKGROUND

Lung cancer is a leading cause of death in United States. A recent study using low dose CT scans for screening long term smokers for lung cancer has, for the first time, demonstrated reduction in mortality, although it is not a standard of care in the community yet.

METHOD

We analyzed lung cancer data for stages 0 through 4 for 1,412 individuals from, a public hospital, Nassau University Medical Center (NUMC) with patients of lower income, two private hospitals, North Shore University Hospital (NSUH) and Long Island Jewish Hospital (LIJ), with patients of higher income, with average household income per year of 83,795 $, 152,777 $ and 93,234 $ respectively.

RESULT

Significantly smaller percentages of patients were diagnosed with stages 0 and 1 lung cancer at NUMC (8.55%) versus either NSUH (36.18%, P < 0.001) or LIJ (35.70%, (P < 0.001).

CONCLUSION

At this point there is evidence that Lung Cancer Screening reduces mortality in long term smokers, but there is debate over, if it should be made into a recommendation. In light of the above study we suggest, that screening for lower socioeconomic class, could be recommended, if not for general population.

摘要

背景

肺癌是美国主要的死亡原因之一。最近一项使用低剂量CT扫描对长期吸烟者进行肺癌筛查的研究首次证明了死亡率的降低,尽管这在社区中尚未成为标准治疗方法。

方法

我们分析了拿骚大学医学中心(NUMC)这家公立医院1412名患者0至4期的肺癌数据,该医院患者收入较低;还分析了北岸大学医院(NSUH)和长岛犹太医院(LIJ)这两家私立医院患者的肺癌数据,这两家医院患者收入较高,平均家庭年收入分别为83,795美元、152,777美元和93,234美元。

结果

NUMC被诊断为0期和1期肺癌的患者比例(8.55%)显著低于NSUH(36.18%,P < 0.001)或LIJ(35.70%,P < 0.001)。

结论

目前有证据表明肺癌筛查可降低长期吸烟者的死亡率,但对于是否应将其作为一项建议存在争议。根据上述研究,我们建议,如果不是针对普通人群,那么可以建议对社会经济阶层较低的人群进行筛查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b6f/5649787/1081a3a3cb13/wjon-03-097-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b6f/5649787/1081a3a3cb13/wjon-03-097-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b6f/5649787/1081a3a3cb13/wjon-03-097-g001.jpg

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