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特邀评论:妊娠期高血压和糖尿病——一个主要的公共卫生关注点。

Invited Commentary: Gestational Hypertension and Diabetes-A Major Public Health Concern.

出版信息

Am J Epidemiol. 2017 Nov 15;186(10):1125-1128. doi: 10.1093/aje/kwx265.

DOI:10.1093/aje/kwx265
PMID:29149254
Abstract

The obesity epidemic in the United States and other countries has contributed to an increase in the rates of gestational diabetes and hypertension. In the past, it was thought that most cases of gestational diabetes and hypertension would resolve after completion of pregnancy. In this issue of the Journal, Pace et al. (Am J Epidemiol. 2017;186(10):1115-1124) clearly documented that both gestational diabetes and hypertension lead to diabetes and hypertension and that the combination of both during pregnancy leads to very high rates of subsequent diabetes and hypertension. A new generation of epidemiology studies using the evolving new technologies and genetics (host susceptibility studies) are needed to improve our understanding of the etiology of gestational diabetes and hypertension. Early identification of women at risk of gestational diabetes and hypertension, better treatment during pregnancy, and preventive and clinical therapies for treatment of diabetes and hypertension after pregnancy are very important for improving women's health and reducing risk of cardiovascular disease later in life.

摘要

美国和其他国家的肥胖症流行导致妊娠糖尿病和高血压的发病率上升。过去,人们认为大多数妊娠糖尿病和高血压病例在妊娠结束后会得到解决。在本期《美国流行病学杂志》上,Pace 等人(Am J Epidemiol. 2017;186(10):1115-1124)明确记录了妊娠糖尿病和高血压都会导致糖尿病和高血压,而且这两种疾病在妊娠期间同时存在会导致极高的后续糖尿病和高血压发病率。需要新一代的流行病学研究,利用不断发展的新技术和遗传学(宿主易感性研究),来提高我们对妊娠糖尿病和高血压病因的理解。早期识别有患妊娠糖尿病和高血压风险的妇女,在妊娠期间进行更好的治疗,以及在妊娠后进行预防和临床治疗以治疗糖尿病和高血压,对于改善妇女的健康和降低日后患心血管疾病的风险非常重要。

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Invited Commentary: Gestational Hypertension and Diabetes-A Major Public Health Concern.特邀评论:妊娠期高血压和糖尿病——一个主要的公共卫生关注点。
Am J Epidemiol. 2017 Nov 15;186(10):1125-1128. doi: 10.1093/aje/kwx265.
2
Gestational diabetes, pregnancy hypertension, and late vascular disease.妊娠期糖尿病、妊娠高血压和晚期血管疾病。
Diabetes Care. 2007 Jul;30 Suppl 2:S246-50. doi: 10.2337/dc07-s224.
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Earlier Age of Onset of Chronic Hypertension and Type 2 Diabetes Mellitus After a Hypertensive Disorder of Pregnancy or Gestational Diabetes Mellitus.妊娠高血压疾病或妊娠期糖尿病后慢性高血压和2型糖尿病发病年龄提前
Hypertension. 2015 Dec;66(6):1116-22. doi: 10.1161/HYPERTENSIONAHA.115.06005. Epub 2015 Oct 12.
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Conjoint Associations of Gestational Diabetes and Hypertension With Diabetes, Hypertension, and Cardiovascular Disease in Parents: A Retrospective Cohort Study.妊娠期糖尿病和高血压与父母患糖尿病、高血压及心血管疾病的联合关联:一项回顾性队列研究。
Am J Epidemiol. 2017 Nov 15;186(10):1115-1124. doi: 10.1093/aje/kwx263.
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Prepregnancy body mass index is an independent risk factor for gestational hypertension, gestational diabetes, preterm labor, and small- and large-for-gestational-age infants.孕前体重指数是妊娠期高血压、妊娠期糖尿病、早产以及小于胎龄儿和大于胎龄儿的独立危险因素。
J Matern Fetal Neonatal Med. 2015;28(14):1679-86. doi: 10.3109/14767058.2014.964675. Epub 2014 Sep 29.
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[Pregnancy complications as a risk factor for metabolic and cardiovascular disease in later life].[妊娠并发症作为晚年代谢和心血管疾病的危险因素]
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Objectively measured short sleep duration and later sleep midpoint in pregnancy are associated with a higher risk of gestational diabetes.客观测量发现,孕期睡眠时间短和睡眠中点较晚与妊娠期糖尿病风险较高有关。
Am J Obstet Gynecol. 2017 Oct;217(4):447.e1-447.e13. doi: 10.1016/j.ajog.2017.05.066. Epub 2017 Jun 7.
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Hypertension in gestational diabetes mellitus: pathophysiology and long-term consequences.妊娠期糖尿病中的高血压:病理生理学与长期后果
J Matern Fetal Neonatal Med. 2010 Mar;23(3):229-33. doi: 10.3109/14767050903550899.
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Second trimester amniotic fluid myo-inositol concentrations in women later developing gestational diabetes mellitus or pregnancy-induced hypertension.孕中期羊水肌醇浓度与随后发生妊娠期糖尿病或妊娠高血压综合征的女性。
J Matern Fetal Neonatal Med. 2016;29(14):2245-7. doi: 10.3109/14767058.2015.1081886. Epub 2015 Sep 12.
10
Dasgupta and Pace Respond to "Gestational Hypertension and Diabetes".达斯古普塔和佩斯回应《妊娠期高血压与糖尿病》。
Am J Epidemiol. 2017 Nov 15;186(10):1129-1130. doi: 10.1093/aje/kwx266.

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