Am J Epidemiol. 2017 Nov 15;186(10):1125-1128. doi: 10.1093/aje/kwx265.
The obesity epidemic in the United States and other countries has contributed to an increase in the rates of gestational diabetes and hypertension. In the past, it was thought that most cases of gestational diabetes and hypertension would resolve after completion of pregnancy. In this issue of the Journal, Pace et al. (Am J Epidemiol. 2017;186(10):1115-1124) clearly documented that both gestational diabetes and hypertension lead to diabetes and hypertension and that the combination of both during pregnancy leads to very high rates of subsequent diabetes and hypertension. A new generation of epidemiology studies using the evolving new technologies and genetics (host susceptibility studies) are needed to improve our understanding of the etiology of gestational diabetes and hypertension. Early identification of women at risk of gestational diabetes and hypertension, better treatment during pregnancy, and preventive and clinical therapies for treatment of diabetes and hypertension after pregnancy are very important for improving women's health and reducing risk of cardiovascular disease later in life.
美国和其他国家的肥胖症流行导致妊娠糖尿病和高血压的发病率上升。过去,人们认为大多数妊娠糖尿病和高血压病例在妊娠结束后会得到解决。在本期《美国流行病学杂志》上,Pace 等人(Am J Epidemiol. 2017;186(10):1115-1124)明确记录了妊娠糖尿病和高血压都会导致糖尿病和高血压,而且这两种疾病在妊娠期间同时存在会导致极高的后续糖尿病和高血压发病率。需要新一代的流行病学研究,利用不断发展的新技术和遗传学(宿主易感性研究),来提高我们对妊娠糖尿病和高血压病因的理解。早期识别有患妊娠糖尿病和高血压风险的妇女,在妊娠期间进行更好的治疗,以及在妊娠后进行预防和临床治疗以治疗糖尿病和高血压,对于改善妇女的健康和降低日后患心血管疾病的风险非常重要。