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Cancer Epidemiol Biomarkers Prev. 2015 Oct;24(10):1548-56. doi: 10.1158/1055-9965.EPI-15-0044. Epub 2015 Jul 29.
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Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement.系统评价与Meta分析方案的首选报告项目（PRISMA-P）2015声明。
Syst Rev. 2015 Jan 1;4(1):1. doi: 10.1186/2046-4053-4-1.
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The burden of human papillomavirus infections and related diseases in sub-saharan Africa.撒哈拉以南非洲地区人乳头瘤病毒感染及相关疾病的负担。
Vaccine. 2013 Dec 29;31 Suppl 5(0 5):F32-46. doi: 10.1016/j.vaccine.2012.07.092.
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"HPV? Never heard of it!": a systematic review of girls' and parents' information needs, views and preferences about human papillomavirus vaccination.“HPV？从未听说过！”：一项关于女孩和家长对人乳头瘤病毒疫苗接种的信息需求、看法和偏好的系统评价。
Vaccine. 2013 Oct 25;31(45):5152-67. doi: 10.1016/j.vaccine.2013.08.091. Epub 2013 Sep 9.
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Sharing a diagnosis of HPV-related head and neck cancer: the emotions, the confusion, and what patients want to know.分享 HPV 相关头颈癌的诊断：情绪、困惑，以及患者想知道的。
Head Neck. 2013 Nov;35(11):1534-41. doi: 10.1002/hed.23182. Epub 2012 Nov 20.
6
Are women ready for the new cervical screening protocol in England? A systematic review and qualitative synthesis of views about human papillomavirus testing.英国新的宫颈癌筛查方案，女性准备好了吗？关于人乳头瘤病毒检测的系统评价和定性综合分析。
Br J Cancer. 2012 Jul 10;107(2):243-54. doi: 10.1038/bjc.2012.256. Epub 2012 Jun 14.
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Success of HPV vaccination is now a matter of coverage.人乳头瘤病毒疫苗接种的成功现在取决于接种覆盖率。
Lancet Oncol. 2012 Jan;13(1):10-2. doi: 10.1016/S1470-2045(11)70324-2. Epub 2011 Nov 8.
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Review of human immunodeficiency virus (HIV) and squamous lesions of the uterine cervix.人类免疫缺陷病毒（HIV）与子宫颈鳞状病变综述。
Diagn Cytopathol. 2011 Jan;39(1):65-72. doi: 10.1002/dc.21364.
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Beyond cervical cancer: burden of other HPV-related cancers among men and women.除宫颈癌之外：男性和女性中 HPV 相关癌症的负担。
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Human Papilloma Virus (HPV) in head and neck region: review of literature.人乳头瘤病毒（HPV）在头颈部：文献综述。
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在撒哈拉以南非洲地区绘制人乳头瘤病毒相关癌症分布证据：范围综述方案。

Mapping evidence on the distribution of human papillomavirus-related cancers in sub-Saharan Africa: scoping review protocol.

机构信息

Discipline of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Mazisi Kunene Road, Durban, 4041, South Africa.

出版信息

Syst Rev. 2017 Nov 17;6(1):229. doi: 10.1186/s13643-017-0623-3.

DOI:10.1186/s13643-017-0623-3
PMID:29149907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5693799/
Abstract

BACKGROUND

Despite the introduction of HPV vaccines, the incidence of HPV-related cancers (cervical, penile, anal, vulvar, vagina, head, and neck) in sub-Saharan Africa has been rising. The increasing incidence of these HPV-related cancers has been attributed to changes in lifestyle-related risk factors, most notably sexual behavior. The main objective of this study is to map evidence on the distribution of HIV-related cancers in sub-Saharan Africa (SSA).

METHODS AND ANALYSIS

We will conduct a scoping review to explore, describe, and map literature on the distribution of HPV-related cancers in sub-Saharan Africa. The primary search will include peer-reviewed and review articles. The list of references from included studies will also be searched. The search will be performed using EBSCOhost platform by searching the following databases within the platform: Academic search complete, health source: nursing/academic edition, CINAHL with full text, PubMed, Science Direct, Google scholar and World Health Organization (WHO) library databases, and gray literature. The researcher will search the articles using keywords, from the included studies; abstract and full articles will be screened by two independent reviewers. The screening will be guided by the inclusion and exclusion criteria. A thematic content analysis will be used to present the narrative account of the reviews, using NVivo version 10.

DISCUSSION

We anticipate finding relevant literature on the distribution of HPV-related cancers in sub-Saharan Africa. The study findings will help reveal research gaps to guide future research.

SYSTEMATIC REVIEW REGISTRATION

PROSPERO CRD42017062403.

摘要

背景

尽管 HPV 疫苗已经问世，但撒哈拉以南非洲地区与 HPV 相关的癌症（宫颈癌、阴茎癌、肛门癌、外阴癌、阴道癌、头颈部癌）的发病率仍在上升。这些 HPV 相关癌症发病率的上升归因于生活方式相关风险因素的变化，尤其是性行为。本研究的主要目的是绘制撒哈拉以南非洲地区（SSA）与 HIV 相关癌症分布的证据图。

方法和分析

我们将进行范围综述，以探索、描述和绘制撒哈拉以南非洲地区 HPV 相关癌症分布的文献图。主要检索将包括同行评议和综述文章。还将搜索纳入研究的参考文献列表。将使用 EBSCOhost 平台在该平台内的以下数据库中进行搜索：学术搜索完整、健康来源：护理/学术版、CINAHL 全文、PubMed、Science Direct、Google 学术和世界卫生组织（WHO）图书馆数据库以及灰色文献。研究人员将使用从纳入研究中获得的关键词搜索文章；摘要和全文将由两名独立评审员筛选。筛选将根据纳入和排除标准进行指导。将使用 NVivo 版本 10 对综述进行主题内容分析，以呈现叙述性描述。

讨论

我们预计会找到有关撒哈拉以南非洲地区 HPV 相关癌症分布的相关文献。研究结果将有助于揭示研究差距，指导未来的研究。

系统评价注册

PROSPERO CRD42017062403。