PET/MR成像：阿尔茨海默病及其他痴呆症的新前沿。
PET/MR Imaging: New Frontier in Alzheimer's Disease and Other Dementias.
作者信息
Zhang Xin Y, Yang Zhen L, Lu Guang M, Yang Gui F, Zhang Long J
机构信息
Medical Imaging Center, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
出版信息
Front Mol Neurosci. 2017 Nov 1;10:343. doi: 10.3389/fnmol.2017.00343. eCollection 2017.
Alzheimer's disease (AD) is the most common form of dementia; a progressive neurodegenerative disease that currently lacks an effective treatment option. Early and accurate diagnosis, in addition to quick elimination of differential diagnosis, allows us to provide timely treatments that delay the progression of AD. Imaging plays an important role for the early diagnosis of AD. The newly emerging PET/MR imaging strategies integrate the advantages of PET and MR to diagnose and monitor AD. This review introduces the development of PET/MR imaging systems, technical considerations of PET/MR imaging, special considerations of PET/MR in AD, and the system's potential clinical applications and future perspectives in AD.
阿尔茨海默病（AD）是最常见的痴呆形式；是一种目前缺乏有效治疗方案的进行性神经退行性疾病。除了快速排除鉴别诊断外，早期准确诊断能让我们提供及时的治疗，延缓AD的进展。影像学在AD的早期诊断中发挥着重要作用。新出现的PET/MR成像策略整合了PET和MR的优势来诊断和监测AD。本文综述介绍了PET/MR成像系统的发展、PET/MR成像的技术考量、PET/MR在AD中的特殊考量，以及该系统在AD中的潜在临床应用和未来前景。
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