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两种流行病的交汇:肥胖学龄儿童维生素D缺乏症

The Convergence of Two Epidemics: Vitamin D Deficiency in Obese School-aged Children.

作者信息

Cheng Linda

机构信息

Columbia University School of Nursing, USA.

出版信息

J Pediatr Nurs. 2018 Jan-Feb;38:20-26. doi: 10.1016/j.pedn.2017.10.005. Epub 2017 Oct 18.

Abstract

PROBLEM

Vitamin D deficiency (VDD) and obesity are two interrelated global epidemics that affect school-aged children. This article will review the relationship between VDD and obesity in school-aged children and implications it has for the pediatric nurse (PN).

ELIGIBILITY CRITERIA

Original articles of studies, review articles and meta-analyses were selected from the past 5years and pooled for review. These included obese school-aged children who had vitamin D insufficiency. The latest guidelines concerning the issue were also included.

SAMPLE

Children 6-12years of age with obesity and vitamin D insufficiency.

RESULTS

This review strongly implies obesity in children being a strong risk factor for VDD. Prevention of VDD starts with lifestyle changes and adequate dietary intake of fortified foods and current screening recommendations for VDD are inconsistent. Vitamin D supplementation is recommended with inadequate intake or deficient serum 25-hydroxyvitamin D levels or signs of hypocalcemia. Supplementation doses differ based on whether VDD is being prevented or being treated and in obese children, the Endocrine Society recommends a dose that is two to three times higher than for normal weight children. Subclinical signs and symptoms of VDD include musculoskeletal pain, fractures, reduced bone density and reduced immunity.

CONCLUSIONS

Whereas obesity is a strong risk factor for VDD, more research is needed to clarify the role of VDD as a risk factor for obesity.

IMPLICATIONS

The PN plays an essential role in preventing, screening for, assessing for, treating and counseling on VDD in obese school-aged children.

摘要

问题

维生素D缺乏症(VDD)和肥胖是影响学龄儿童的两种相互关联的全球性流行病。本文将综述学龄儿童中VDD与肥胖之间的关系及其对儿科护士(PN)的影响。

纳入标准

从过去5年中选取原始研究文章、综述文章和荟萃分析进行汇总审查。这些研究对象包括患有维生素D不足的肥胖学龄儿童。还纳入了有关该问题的最新指南。

样本

6至12岁患有肥胖症和维生素D不足的儿童。

结果

本综述强烈表明儿童肥胖是VDD的一个重要危险因素。预防VDD应从改变生活方式和充分摄入富含维生素D的食物开始,而目前关于VDD的筛查建议并不一致。当摄入量不足、血清25-羟基维生素D水平缺乏或出现低钙血症迹象时,建议补充维生素D。补充剂量因预防还是治疗VDD而异,对于肥胖儿童,内分泌学会建议的剂量比正常体重儿童高两到三倍。VDD的亚临床症状和体征包括肌肉骨骼疼痛、骨折、骨密度降低和免疫力下降。

结论

虽然肥胖是VDD的一个重要危险因素,但需要更多研究来阐明VDD作为肥胖危险因素的作用。

启示

儿科护士在肥胖学龄儿童VDD的预防、筛查、评估、治疗和咨询方面发挥着重要作用。

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