Chan Hui Bin Yvonne, How Choon How, Ng Chung Wai Mark
Care and Health Integration, Changi General Hospital, Singapore.
SingHealth Polyclinics, Singapore.
Singapore Med J. 2017 Nov;58(11):632-635. doi: 10.11622/smedj.2017100.
Dengue is a mosquito-borne viral disease that has established itself globally in both endemic and epidemic transmission cycles. While diagnostic decision-making for dengue is often guided by clinical judgement, definitive laboratory tests, including rapid point-of-care tests, have many advantages in the primary care setting. These include providing epidemiological data and diagnostic clarity for atypical cases, as well as contributing to patient education and compliance. This article discussed the types of diagnostic methods for dengue, when to use them and the appropriateness of each test. Viral detection diagnostic methods such as NS1 antigen assays are generally used within the first week of illness onset, whereas dengue serology testing is most appropriate after that time frame. Locally available rapid point-of-care tests, which include both assays in one convenient test kit, can enhance dengue diagnosis in an endemic setting.
登革热是一种由蚊子传播的病毒性疾病，已在全球范围内通过地方流行和流行传播周期确立了自身地位。虽然登革热的诊断决策通常由临床判断指导，但确定性实验室检测，包括快速即时检测，在初级保健环境中有许多优势。这些优势包括为非典型病例提供流行病学数据和诊断清晰度，以及有助于患者教育和依从性。本文讨论了登革热的诊断方法类型、何时使用这些方法以及每种检测的适用性。诸如NS1抗原检测等病毒检测诊断方法通常在发病后的第一周内使用，而登革热血清学检测在该时间段之后最为合适。本地可用的快速即时检测，包括在一个方便的检测试剂盒中的两种检测方法，可以在地方流行环境中加强登革热的诊断。
