Department of Biotechnology, SRM Institute of Science and Technology, College of Engineering and Technology, SRM Nagar, Kattankulathur, Kanchipuram, Chennai 603203, India.
Department of Biotechnology, National Institute of Technology, Arunachal Pradesh 791109, India.
Biosensors (Basel). 2023 Mar 6;13(3):349. doi: 10.3390/bios13030349.
Every year, the dengue virus and its principal mosquito vector, sp., have caused massive outbreaks, primarily in equatorial countries. The pre-existing techniques available for dengue detection are expensive and require trained personnel. Graphene and its derivatives have remarkable properties of electrical and thermal conductivity, and are flexible, light, and biocompatible, making them ideal platforms for biosensor development. The incorporation of these materials, along with appropriate nanomaterials, improves the quality of detection methods. Graphene can help overcome the difficulties associated with conventional techniques. In this review, we have given comprehensive details on current graphene-based diagnostics for dengue virus detection. We have also discussed state-of-the-art biosensing technologies and evaluated the advantages and disadvantages of the same.
每年,登革热病毒及其主要媒介——埃及伊蚊,都会在赤道国家引发大规模疫情。现有的登革热检测技术昂贵且需要经过培训的人员。石墨烯及其衍生物具有出色的导电性和导热性,同时还具有柔韧性、轻便和生物兼容性,是生物传感器开发的理想平台。将这些材料与适当的纳米材料结合使用,可以提高检测方法的质量。石墨烯可以帮助克服传统技术的困难。在这篇综述中,我们全面介绍了基于石墨烯的登革热病毒检测的最新诊断方法。我们还讨论了最先进的生物传感技术,并评估了它们的优缺点。