1 Department of Oral and Maxillofacial Radiology, Osaka University Graduate School of Dentistry , Suita, Osaka , Japan.
2 Section of Oral and Maxillofacial Radiology, UCLA School of Dentistry , Los Angeles, CA , USA.
Dentomaxillofac Radiol. 2018 Feb;47(3):20170290. doi: 10.1259/dmfr.20170290. Epub 2017 Dec 15.
To evaluate the impact of cone beam CT (CBCT) in the diagnostic thinking efficacy, management and prognosis of patients with suspected Stage 0 medication-related osteonecrosis of the jaw (MRONJ).
For 15 patients with suspected Stage 0 MRONJ, clinical photographs, a panoramic radiograph and selected CBCT sections were identified. 13 oral surgeons reviewed the material and answered 10 questions in two different sessions. First session included clinical photographs and panoramic radiographs, while second session also included CBCT images. Questions (Qs) referred to dental disease and bone abnormalities (Qs 1, 2 and 3), differential diagnosis (Qs 4 and 5), patient management (Qs 6 and 7) and prognosis (Qs 8 and 9). Q 10 queried indication (first session) and usefulness (second session) of CBCT images.
Qs 2, 3, 5, 7 and 9 scores increased between sessions, with statistical differences for Qs 2, 3, 5 and 7 (<0.05). Patients 2, 8 and 11 showed a significant increase in the average score of all Qs between sessions, while scores for patient 10 nearly reached statistical significance (p = 0.055). For Q 10, 57.4% of answers reported that CBCT was needed (first session) and was beneficial (second session).
CBCT had a significant impact in differential diagnosis and management of patients with suspected Stage 0 MRONJ.
评估锥形束 CT(CBCT)在疑似 0 期药物相关性下颌骨坏死(MRONJ)患者的诊断思维效果、管理和预后中的影响。
对 15 名疑似 0 期 MRONJ 的患者,确定了临床照片、全景片和选定的 CBCT 片。13 名口腔外科医生在两个不同的阶段回顾了材料并回答了 10 个问题。第一阶段包括临床照片和全景片,而第二阶段还包括 CBCT 图像。问题(Qs)涉及牙齿疾病和骨骼异常(Qs1、2 和 3)、鉴别诊断(Qs4 和 5)、患者管理(Qs6 和 7)和预后(Qs8 和 9)。问题 10 询问 CBCT 图像的适应症(第一阶段)和有用性(第二阶段)。
Qs2、3、5、7 和 9 的分数在两个阶段之间有所增加,Qs2、3、5 和 7 具有统计学差异(<0.05)。患者 2、8 和 11 在所有 Qs 的平均分数上在两个阶段之间都有显著增加,而患者 10 的分数几乎达到统计学意义(p=0.055)。对于问题 10,57.4%的回答报告 CBCT 是需要的(第一阶段)并且是有益的(第二阶段)。
CBCT 对疑似 0 期 MRONJ 患者的鉴别诊断和管理有显著影响。