Russo Giacomo, Barbato Francesco, Cardone Eleonora, Fattore Margherita, Albrizio Stefania, Grumetto Lucia
a Dipartimento di Farmacia , Scuola di Medicina e Chirurgia, Università degli Studi di Napoli Federico II , Via D. Montesano, Naples , Italy.
b Consorzio Interuniversitario INBB, Viale Medaglie d'Oro , Rome , Italy.
J Environ Sci Health B. 2018 Feb 1;53(2):116-120. doi: 10.1080/03601234.2017.1388662. Epub 2017 Nov 27.
A simple and sensitive validated analytical method based on liquid chromatography coupled to tandem fluorescence (FD) and ultraviolet (UV) spectrophotometry was applied to monitor the presence of bisphenol A and bisphenol S in plastic baby bottles marketed in Italy. The limits of detection (LOD) were 3.75 ng mL and 80.00 ng mL, and those of quantification (LOQ) were 12.51 ng mL and 260.00 ng mL for BPA (FD detection) and for BPS (UV detection), respectively. BPA was found in only four samples, two samples undergone to microwave heating and two samples undergone to bottle warmer heating either at 40°C or at 80°C. Although the quantities of leached BPA were well below the reference dose for daily intake established by the European Food Safety Authority (EFSA) (4.0 µg kg bw/day), the release of BPA and BPS from these plastic materials should be carefully considered by the government authorities to increase people's awareness on this issue and to protect the most vulnerable population group.
一种基于液相色谱联用串联荧光（FD）和紫外（UV）分光光度法的简单且灵敏的经过验证的分析方法，被用于监测在意大利市场上销售的塑料婴儿奶瓶中双酚A和双酚S的存在情况。双酚A（FD检测）和双酚S（UV检测）的检测限（LOD）分别为3.75 ng/mL和80.00 ng/mL，定量限（LOQ）分别为12.51 ng/mL和260.00 ng/mL。仅在四个样品中检测到双酚A，其中两个样品经过微波加热，另外两个样品在40°C或80°C下使用奶瓶加热器加热。尽管浸出的双酚A的量远低于欧洲食品安全局（EFSA）确定的每日摄入量参考剂量（4.0 μg/kg bw/天），但政府当局应仔细考虑这些塑料材料中双酚A和双酚S的释放情况，以提高人们对该问题的认识，并保护最脆弱的人群。
