• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项针对儿童烧伤瘢痕治疗方法的系统评价:根据临床研究评估疗效、安全性、标准方案、平均疗程和耐受性。

A systematic review of procedural treatments for burn scars in children: Evaluating efficacy, safety, standard protocols, average sessions and tolerability based on clinical studies.

机构信息

Department of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.

出版信息

Int Wound J. 2024 Oct;21(10):e70091. doi: 10.1111/iwj.70091.

DOI:10.1111/iwj.70091
PMID:39379072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11461021/
Abstract

Managing burn scars in children presents significant challenges. This study investigates effective treatment methods for burn scars, focusing on efficacy, safety, standard protocols and tolerability. Major databases such as PubMed, Scopus and Web of Science were thoroughly searched up to August 2024, emphasizing procedural treatments for burn scars in children. Key data collected included participant demographics, sample sizes, intervention methods, follow-up protocols, treatment effectiveness and reported adverse events. A total of 256 children were assessed, with all procedural treatments yielding satisfactory outcomes. Among the various methods, trapeze-flap plasty and percutaneous collagen induction showed improvements in all patients. In the laser treatment group, which included 161 children, the Vancouver Scar Scale (VSS) score reduction ranged from 55.55% to 76.31%, with outcomes rated as good (24.61%) to excellent (60%). Laser treatment using local anaesthesia proved to be well tolerated by children. Our findings indicate that various methods-including trapeze-flap plasty, percutaneous collagen induction, phototherapy and fractional CO laser-demonstrate a relatively good response and an acceptable safety profile. Notably, light-based therapies/lasers may serve as safe, effective and tolerable options for scar treatment in this age group, often eliminating the need for general anaesthesia.

摘要

管理儿童烧伤疤痕面临重大挑战。本研究调查了烧伤疤痕的有效治疗方法,重点关注疗效、安全性、标准方案和耐受性。截至 2024 年 8 月,我们彻底搜索了 PubMed、Scopus 和 Web of Science 等主要数据库,重点关注儿童烧伤疤痕的程序治疗。收集的主要数据包括参与者的人口统计学、样本量、干预方法、随访方案、治疗效果和报告的不良事件。共有 256 名儿童接受了评估,所有程序治疗均取得了满意的结果。在各种方法中,吊带皮瓣成形术和经皮胶原诱导术在所有患者中均显示出改善。在包括 161 名儿童的激光治疗组中,温哥华疤痕量表(VSS)评分降低范围为 55.55%至 76.31%,结果评为良好(24.61%)至优秀(60%)。局部麻醉下的激光治疗被证明被儿童很好地耐受。我们的研究结果表明,各种方法,包括吊带皮瓣成形术、经皮胶原诱导术、光疗和分束 CO2 激光,均表现出相对较好的反应和可接受的安全性。值得注意的是,基于光的疗法/激光可能是该年龄段疤痕治疗的安全、有效和耐受的选择,通常无需全身麻醉。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f10/11461021/af7542edca84/IWJ-21-e70091-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f10/11461021/af7542edca84/IWJ-21-e70091-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f10/11461021/af7542edca84/IWJ-21-e70091-g001.jpg

相似文献

1
A systematic review of procedural treatments for burn scars in children: Evaluating efficacy, safety, standard protocols, average sessions and tolerability based on clinical studies.一项针对儿童烧伤瘢痕治疗方法的系统评价:根据临床研究评估疗效、安全性、标准方案、平均疗程和耐受性。
Int Wound J. 2024 Oct;21(10):e70091. doi: 10.1111/iwj.70091.
2
Early intervention by Z-plasty combined with fractional CO laser therapy as a potential treatment for hypertrophic burn scars.Z 成形术联合分束 CO2 激光治疗肥厚性烧伤瘢痕的早期干预。
J Plast Reconstr Aesthet Surg. 2021 Nov;74(11):3087-3093. doi: 10.1016/j.bjps.2021.03.079. Epub 2021 Apr 20.
3
A new CO2 laser technique for the treatment of pediatric hypertrophic burn scars: An observational study.一种用于治疗小儿肥厚性烧伤瘢痕的新型二氧化碳激光技术:一项观察性研究。
Medicine (Baltimore). 2016 Oct;95(42):e5168. doi: 10.1097/MD.0000000000005168.
4
The efficacy and safety of fractional CO laser therapy in the treatment of burn scars: A meta-analysis.分次二氧化碳激光治疗烧伤瘢痕的疗效与安全性:一项荟萃分析。
Burns. 2021 Nov;47(7):1469-1477. doi: 10.1016/j.burns.2021.08.010. Epub 2021 Aug 20.
5
Fractional CO2 Laser Treatment Outcomes for Pediatric Hypertrophic Burn Scars.小儿增生性烧伤瘢痕的二氧化碳点阵激光治疗效果
J Burn Care Res. 2019 Jun 21;40(4):386-391. doi: 10.1093/jbcr/irz046.
6
Evaluation of the efficacy, safety and satisfaction rates of platelet-rich plasma, non-cross-linked hyaluronic acid and the combination of platelet-rich plasma and non-cross-linked hyaluronic acid in patients with burn scars treated with fractional CO laser: A randomized controlled clinical trial.富血小板血浆、非交联透明质酸及富血小板血浆联合非交联透明质酸治疗分束 CO2 激光治疗烧伤瘢痕患者的疗效、安全性和满意度评估:一项随机对照临床试验。
Int Wound J. 2024 Oct;21(10):e70065. doi: 10.1111/iwj.70065.
7
Laser in the management of burn scars.激光在烧伤瘢痕治疗中的应用
Burns. 2017 Nov;43(7):1379-1389. doi: 10.1016/j.burns.2017.07.001. Epub 2017 Aug 4.
8
Combination treatment utilizing fractional ablative and continuous wave CO lasers for hypertrophic burn scars.利用分段式消融和连续波 CO 激光联合治疗增生性烧伤瘢痕。
Burns. 2021 Aug;47(5):1084-1093. doi: 10.1016/j.burns.2020.10.015. Epub 2020 Nov 7.
9
Laser resurfacing and remodeling of hypertrophic burn scars: the results of a large, prospective, before-after cohort study, with long-term follow-up.激光磨削与重塑肥厚性烧伤瘢痕:一项大型前瞻性前后队列研究的结果及长期随访
Ann Surg. 2014 Sep;260(3):519-29; discussion 529-32. doi: 10.1097/SLA.0000000000000893.
10
Hypertrophic Scar Improvement by Early Intervention With Ablative Fractional Carbon Dioxide Laser Treatment.早期采用消融性二氧化碳点阵激光治疗改善增生性瘢痕。
Lasers Surg Med. 2021 Apr;53(4):450-457. doi: 10.1002/lsm.23301. Epub 2020 Jul 16.

引用本文的文献

1
Effect of Topical Timolol on Healing of Immature Breast Scars After Mammoplasty: A Randomized Controlled Trial With Blinded Assessors and Patients.局部用噻吗洛尔对乳房成形术后未成熟乳房瘢痕愈合的影响:一项评估者和患者双盲的随机对照试验
J Cosmet Dermatol. 2025 Jun;24(6):e70261. doi: 10.1111/jocd.70261.
2
"Acne vulgaris: key insights, treatment, and future prospects".寻常痤疮:关键见解、治疗方法及未来展望
Mol Divers. 2025 May 16. doi: 10.1007/s11030-025-11209-3.
3
Exploring the dermatological applications of human mesenchymal stem cell secretome: a comprehensive review.

本文引用的文献

1
The efficacy, satisfaction, and safety of carbon dioxide (CO2) fractional laser in combination with pulsed dye laser (PDL) versus each one alone in the treatment of hypertrophic burn scars: a single-blinded randomized controlled trial.二氧化碳(CO2)点阵激光联合脉冲染料激光(PDL)与单独使用两者之一治疗增生性烧伤瘢痕的疗效、满意度和安全性:一项单盲随机对照试验。
Lasers Med Sci. 2024 Feb 20;39(1):69. doi: 10.1007/s10103-024-03976-6.
2
A systematic review of the efficacy, safety and satisfaction of regenerative medicine treatments, including platelet-rich plasma, stromal vascular fraction and stem cell-conditioned medium for hypertrophic scars and keloids.一项关于再生医学治疗肥厚性瘢痕和瘢痕疙瘩的疗效、安全性和满意度的系统评价,包括富含血小板的血浆、基质血管成分和干细胞条件培养基。
Int Wound J. 2024 Apr;21(4):e14557. doi: 10.1111/iwj.14557. Epub 2023 Dec 21.
3
探索人间充质干细胞分泌组的皮肤病学应用:一项综述
Stem Cell Res Ther. 2025 Apr 12;16(1):177. doi: 10.1186/s13287-025-04311-8.
4
Impact of pentoxifylline on efficacy, safety, tolerability, and treatment satisfaction of fractional carbon dioxide laser in patients with burn scars: a pilot blinded randomized controlled trial.己酮可可碱对烧伤瘢痕患者二氧化碳点阵激光疗效、安全性、耐受性及治疗满意度的影响:一项前瞻性双盲随机对照试验
Lasers Med Sci. 2025 Apr 3;40(1):174. doi: 10.1007/s10103-025-04328-8.
Efficacy of fractional CO laser in combination with stromal vascular fraction (SVF) compared with fractional CO laser alone in the treatment of burn scars: a randomized controlled clinical trial.分比 CO2 激光联合基质血管成分(SVF)与单纯分比 CO2 激光治疗烧伤瘢痕的疗效比较:一项随机对照临床试验。
Stem Cell Res Ther. 2023 Sep 23;14(1):269. doi: 10.1186/s13287-023-03480-8.
4
Beneath the Surface: A Review of Laser Remodeling of Hypertrophic Scars and Burns.深入探讨:肥厚性瘢痕与烧伤的激光重塑综述
Adv Wound Care (New Rochelle). 2019 Apr 1;8(4):168-176. doi: 10.1089/wound.2018.0857. Epub 2019 Apr 3.
5
A new approach in the treatment of pediatric hypertrophic burn scars: Tixel-associated topical triamcinolone acetonide and 5-fluorouracil delivery.一种治疗小儿肥厚性烧伤瘢痕的新方法:微剥脱点阵铒激光联合曲安奈德和 5-氟尿嘧啶局部给药。
J Cosmet Dermatol. 2020 Jan;19(1):131-134. doi: 10.1111/jocd.13192. Epub 2019 Oct 19.
6
Electrophotobiomodulation in the treatment of facial post-burn hypertrophic scars in pediatric patients.电光生物调节疗法治疗小儿面部烧伤后增生性瘢痕
Ann Burns Fire Disasters. 2018 Jun 30;31(2):127-132.
7
Fractional Carbon Dioxide Laser Resurfacing in Combination With Potent Topical Corticosteroids for Hypertrophic Burn Scars in the Pediatric Age Group: An Open Label Study.二氧化碳分次激光磨皮联合强效外用皮质类固醇治疗小儿烧伤后增生性瘢痕:一项开放标签研究
Dermatol Surg. 2018 Aug;44(8):1102-1108. doi: 10.1097/DSS.0000000000001413.
8
Photobiomodulation effect on children's scars.光生物调节对儿童瘢痕的影响。
Lasers Med Sci. 2018 Apr;33(3):497-501. doi: 10.1007/s10103-017-2387-3. Epub 2017 Nov 24.
9
Percutaneous collagen induction as an additive treatment for scar formation following thermal injuries: Preliminary experience in 47 children.经皮胶原诱导作为热损伤后瘢痕形成的辅助治疗:47例儿童的初步经验
Burns. 2017 Aug;43(5):1097-1102. doi: 10.1016/j.burns.2017.02.006. Epub 2017 Mar 7.
10
A new CO2 laser technique for the treatment of pediatric hypertrophic burn scars: An observational study.一种用于治疗小儿肥厚性烧伤瘢痕的新型二氧化碳激光技术:一项观察性研究。
Medicine (Baltimore). 2016 Oct;95(42):e5168. doi: 10.1097/MD.0000000000005168.