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一项针对儿童烧伤瘢痕治疗方法的系统评价:根据临床研究评估疗效、安全性、标准方案、平均疗程和耐受性。

A systematic review of procedural treatments for burn scars in children: Evaluating efficacy, safety, standard protocols, average sessions and tolerability based on clinical studies.

机构信息

Department of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.

出版信息

Int Wound J. 2024 Oct;21(10):e70091. doi: 10.1111/iwj.70091.

Abstract

Managing burn scars in children presents significant challenges. This study investigates effective treatment methods for burn scars, focusing on efficacy, safety, standard protocols and tolerability. Major databases such as PubMed, Scopus and Web of Science were thoroughly searched up to August 2024, emphasizing procedural treatments for burn scars in children. Key data collected included participant demographics, sample sizes, intervention methods, follow-up protocols, treatment effectiveness and reported adverse events. A total of 256 children were assessed, with all procedural treatments yielding satisfactory outcomes. Among the various methods, trapeze-flap plasty and percutaneous collagen induction showed improvements in all patients. In the laser treatment group, which included 161 children, the Vancouver Scar Scale (VSS) score reduction ranged from 55.55% to 76.31%, with outcomes rated as good (24.61%) to excellent (60%). Laser treatment using local anaesthesia proved to be well tolerated by children. Our findings indicate that various methods-including trapeze-flap plasty, percutaneous collagen induction, phototherapy and fractional CO laser-demonstrate a relatively good response and an acceptable safety profile. Notably, light-based therapies/lasers may serve as safe, effective and tolerable options for scar treatment in this age group, often eliminating the need for general anaesthesia.

摘要

管理儿童烧伤疤痕面临重大挑战。本研究调查了烧伤疤痕的有效治疗方法,重点关注疗效、安全性、标准方案和耐受性。截至 2024 年 8 月,我们彻底搜索了 PubMed、Scopus 和 Web of Science 等主要数据库,重点关注儿童烧伤疤痕的程序治疗。收集的主要数据包括参与者的人口统计学、样本量、干预方法、随访方案、治疗效果和报告的不良事件。共有 256 名儿童接受了评估,所有程序治疗均取得了满意的结果。在各种方法中,吊带皮瓣成形术和经皮胶原诱导术在所有患者中均显示出改善。在包括 161 名儿童的激光治疗组中,温哥华疤痕量表(VSS)评分降低范围为 55.55%至 76.31%,结果评为良好(24.61%)至优秀(60%)。局部麻醉下的激光治疗被证明被儿童很好地耐受。我们的研究结果表明,各种方法,包括吊带皮瓣成形术、经皮胶原诱导术、光疗和分束 CO2 激光,均表现出相对较好的反应和可接受的安全性。值得注意的是,基于光的疗法/激光可能是该年龄段疤痕治疗的安全、有效和耐受的选择,通常无需全身麻醉。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f10/11461021/af7542edca84/IWJ-21-e70091-g001.jpg

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