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性别和环境在调节因睡眠不足导致的体重增加方面的作用。

Role of Sex and the Environment in Moderating Weight Gain Due to Inadequate Sleep.

机构信息

Department of Nutritional Sciences, University of Arizona, 1177 E 4th Street Shantz building room 330A, Tucson, AZ, 85721, USA.

Physiological Sciences Graduate Interdisciplinary Program, University of Arizona, 1177 E 4th Street Shantz building room 330A, Tucson, AZ, 85721, USA.

出版信息

Curr Obes Rep. 2017 Dec;6(4):397-404. doi: 10.1007/s13679-017-0290-7.

DOI:10.1007/s13679-017-0290-7
PMID:29181707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6886373/
Abstract

PURPOSE OF REVIEW

The growing prevalence of obesity, inadequate sleep and sleep disorders together with the negative impact of lack of sleep on overall health highlights the need for therapies targeted towards weight gain due to sleep loss.

RECENT FINDINGS

Sex disparities in obesity and sleep disorders are present; yet, the role of sex is inadequately addressed and thus it is unclear whether sensitivity to sleep disruption differs between men and women. Like sex, environmental factors contribute to the development of obesity and poor sleep. The obesogenic environment is characterized by easy access to palatable foods and a low demand for energy expenditure in daily activities. These and other environmental factors are discussed, as they drive altered sleep or their interaction with food choice and intake can promote obesity. We discuss data that suggest differences in sleep patterns and responses to sleep disruption influence sex disparities in weight gain, and that enviromental disturbances alter sleep and interact with features of the obesogenic environment that together promote obesity.

摘要

目的综述

肥胖症、睡眠不足和睡眠障碍的发病率不断上升,以及睡眠不足对整体健康的负面影响,突显了针对因睡眠缺失而导致体重增加的治疗方法的必要性。

最近的发现

肥胖症和睡眠障碍存在性别差异;然而,性别因素没有得到充分的重视,因此尚不清楚睡眠中断对男性和女性的敏感性是否存在差异。与性别一样,环境因素也会导致肥胖和睡眠质量差。致肥胖环境的特点是容易获得美味的食物,日常活动中对能量消耗的需求较低。这些和其他环境因素将被讨论,因为它们会导致睡眠改变,或者它们与食物选择和摄入的相互作用会促进肥胖。我们将讨论一些数据,这些数据表明,睡眠模式的差异和对睡眠中断的反应会影响体重增加方面的性别差异,并且环境干扰会改变睡眠,并与致肥胖环境的特征相互作用,共同促进肥胖。

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本文引用的文献

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Obesity (Silver Spring). 2017 Oct;25(10):1716-1722. doi: 10.1002/oby.21944. Epub 2017 Aug 17.
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Effects of a free-choice high-fat high-sugar diet on brain PER2 and BMAL1 protein expression in mice.自由选择高脂肪高糖饮食对小鼠大脑 PER2 和 BMAL1 蛋白表达的影响。
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Social jet-lag potentiates obesity and metabolic syndrome when combined with cafeteria diet in rats.
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Metabolism. 2017 Jul;72:83-93. doi: 10.1016/j.metabol.2017.04.006. Epub 2017 Apr 18.
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