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芬兰和爱沙尼亚女性乳腺癌患者的生存率:诊断时的分期是两国生存率差异的重要决定因素。

Survival of female breast cancer patients in Finland and in Estonia: stage at diagnosis important determinant of the difference between countries.

作者信息

Karjalainen S, Aareleid T, Hakulinen T, Pukkala E, Rahu M, Tekkel M

机构信息

Finnish Cancer Registry, Helsinki.

出版信息

Soc Sci Med. 1989;28(3):233-8. doi: 10.1016/0277-9536(89)90266-9.

DOI:10.1016/0277-9536(89)90266-9
PMID:2919310
Abstract

The survival experiences of female breast cancer patients diagnosed in 1968-81 in Finland and in Estonia were compared. The series consisted of 18,729 patients in Finland and 4100 in Estonia. The overall estimated 5-year relative survival rate was 67.3% in Finland and 55.9% in Estonia. The stage-adjusted 5-year relative survival rate in Estonia was 63.4% (the Finnish rates used as a standard). Older patients in Finland had much higher survival rates than older patients in Estonia. There was a clear difference in the stage distribution in Estonia between older and younger age groups, with non-localized cases occurring in older age groups. No such difference was noticed in Finland. It seems that the diagnostic lag for older women is longer in Estonia than in Finland. In Estonia older patients seek medical assistance later, or symptoms and signs of younger patients are more effectively studied.

摘要

对芬兰和爱沙尼亚1968年至1981年确诊的女性乳腺癌患者的生存经历进行了比较。芬兰的病例系列包括18729名患者,爱沙尼亚为4100名。芬兰的总体估计5年相对生存率为67.3%,爱沙尼亚为55.9%。以芬兰的发病率为标准,爱沙尼亚经分期调整后的5年相对生存率为63.4%。芬兰的老年患者生存率远高于爱沙尼亚的老年患者。爱沙尼亚老年和年轻年龄组的分期分布存在明显差异,非局限性病例出现在老年组。在芬兰未发现此类差异。似乎爱沙尼亚老年女性的诊断延迟比芬兰更长。在爱沙尼亚,老年患者寻求医疗帮助的时间较晚,或者对年轻患者症状和体征的研究更有效。

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