National Institute of Occupational Health, P.O. Box 8149 Dep, 0033, Oslo, Norway.
Municipality of Horten, P.O. Box 10, 3191, Horten, Norway.
Int Arch Occup Environ Health. 2018 Apr;91(3):317-326. doi: 10.1007/s00420-017-1281-4. Epub 2017 Dec 1.
The aim of this study was to assess short-term changes in pulmonary function in drill floor workers currently exposed to airborne contaminants generated as a result of drilling offshore. We also aimed to study the prevalence of pulmonary fibrosis using high-resolution computed tomography (HRCT) scans of another group of previously exposed drill floor workers.
Pulmonary function was measured before and after a 14-day work period in a follow-up study of 65 drill floor workers and 65 referents. Additionally, 57 other drill floor workers exposed to drilling fluids during the 1980s were examined with HRCT of the lungs in a cross-sectional study.
The drill floor workers had a statistically significant decline in forced expiratory volume in 1 s (FEV) across the 14-day work period after adjustment for diurnal variations in pulmonary function (mean 90 mL, range 30-140 mL), while the small decline among the referents (mean 20 mL, range - 30 to 70 mL) was not of statistical significance. Larger declines in FEV among drill workers were associated with the fewer number of days of active drilling. There were no signs of pulmonary fibrosis related to oil mist exposure among the other previously exposed drill floor workers.
After 14 days offshore, a statistically significant decline in FEV was observed in the drill floor workers, which may not be related to oil mist exposure. No pulmonary fibrosis related to oil mist exposure was observed.
本研究旨在评估目前暴露于海上钻井过程中产生的空气污染物的钻台工人的短期肺功能变化。我们还旨在通过对另一组先前暴露于钻台工人的高分辨率计算机断层扫描（HRCT）扫描来研究肺纤维化的患病率。
在一项对 65 名钻台工人和 65 名对照者的随访研究中，在 14 天的工作期间前后测量了肺功能。此外，在一项横断面研究中，对 57 名在 20 世纪 80 年代接触钻井液的其他钻台工人进行了肺部 HRCT 检查。
在调整肺功能的昼夜变化后，钻台工人在 14 天的工作期间内用力呼气量（FEV）有统计学意义的下降（平均 90 毫升，范围 30-140 毫升），而对照组的小下降（平均 20 毫升，范围-30 至 70 毫升）则无统计学意义。在钻工中，FEV 的较大下降与活跃钻井天数较少有关。在其他先前暴露于钻台的工人中，没有与油雾暴露相关的肺纤维化迹象。
在海上 14 天后，钻台工人的 FEV 出现了统计学上的显著下降，这可能与油雾暴露无关。没有观察到与油雾暴露相关的肺纤维化。
