Skyberg K, Rønneberg A, Kamøy J I, Dale K, Borgersen A
Environ Res. 1986 Aug;40(2):261-73. doi: 10.1016/s0013-9351(86)80102-5.
Twenty-five cable plant workers exposed to mists and vapors of mineral oils and kerosene for 5-35 years have been investigated in a cross-sectional, matched pairs study. The exposed cohort and the referents were examined by radiology, pulmonary function measurements, and a questionnaire for symptoms of respiratory disease. Lung tissue from a deceased worker with 35 years of exposure was investigated by histopathologic methods and by scanning electron microscopy. Exposure measurements were performed by personal sampling. Previous employment and smoking habits were recorded for all subjects. An increased prevalence of slight basal lung fibrosis was found in chest films of the exposed workers. Pulmonary fibrosis was confirmed histopathologically. A moderately decreased vital capacity (VC) and forced expiratory volume (FEV1) was found. Oil mist was measured to time-weighted average levels of 0.15-0.30 mg/m3 with short-term vapor exposure of up to 4000 mg/m3. It is concluded that mists and vapors from petroleum distillates are the most probable causes of the findings.
在一项横断面配对研究中，对25名接触矿物油和煤油雾气及蒸气达5至35年的电缆厂工人进行了调查。通过放射学检查、肺功能测量以及一份关于呼吸道疾病症状的问卷，对暴露队列和对照对象进行了检查。采用组织病理学方法和扫描电子显微镜对一名有35年暴露史的已故工人的肺组织进行了研究。通过个人采样进行暴露测量。记录了所有受试者以前的工作经历和吸烟习惯。在暴露工人的胸部X光片中发现轻度基底肺纤维化的患病率增加。组织病理学证实存在肺纤维化。发现肺活量（VC）和用力呼气量（FEV1）适度下降。测得油雾的时间加权平均水平为0.15至0.30毫克/立方米，短期蒸气暴露量高达4000毫克/立方米。得出的结论是，石油馏出物的雾气和蒸气很可能是这些发现的原因。
