Wang Dongming, Zhou Min, Li Wenzhen, Kong Weijia, Wang Zhichao, Guo Yanjun, Zhang Xiaomin, He Meian, Guo Huan, Chen Weihong
Department of Occupational & Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Department of Occupational Health, Wuhan Prevention and Treatment Center for Occupational Diseases, Wuhan, Hubei, China; Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, Hubei, China.
Department of Occupational & Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
J Am Soc Hypertens. 2018 Feb;12(2):71-79.e5. doi: 10.1016/j.jash.2017.11.001. Epub 2017 Nov 13.
The association between occupational noise exposure and hypertension is unclear. We aimed to explore the association in a Chinese population and to summarize our findings with previous published articles. The cross-sectional study included 22,450 participants from Dongfeng-Tongji Cohort Study. In a subsample of 10,636 subjects, we assessed the association between hearing loss and hypertension. For the meta-analysis, we searched PubMed and EMBASE until April 2017, and the pooled odds ratio (OR) was combined using a random effect model. Compared with participants without occupational noise exposure, the risk of hypertension was significantly higher for noise exposure duration ≥20 (OR = 1.09, 95% confidence interval [CI] = 1.00-1.18). In the sex-specific analysis, the association was only significantly pronounced in males (OR = 1.16, 95% CI = 1.03-1.31), but not in females (OR = 1.01, 95% CI = 0.88-1.14). In the subsample analyses, hearing loss, which was an indicator for exposure to loud noise, was associated with a higher risk of hypertension, especially for participants who were bilateral hearing loss (OR = 1.39, 95% CI = 1.24-1.54). In the meta-analysis, the pooled OR for the association between occupational noise exposure and hypertension was 1.25 (95% CI = 1.10-1.42). On the basis of an indicator for exposure to occupational noise, the cross-sectional study and meta-analysis identified occupational noise exposure as a potential risk factor for increased hypertension risk.
职业性噪声暴露与高血压之间的关联尚不清楚。我们旨在探讨中国人群中的这种关联，并将我们的研究结果与先前发表的文章进行总结。这项横断面研究纳入了东风-同济队列研究的22450名参与者。在10636名受试者的子样本中，我们评估了听力损失与高血压之间的关联。对于荟萃分析，我们检索了截至2017年4月的PubMed和EMBASE，并使用随机效应模型合并汇总比值比（OR）。与无职业性噪声暴露的参与者相比，噪声暴露持续时间≥20年者患高血压的风险显著更高（OR = 1.09，95%置信区间[CI] = 1.00-1.18）。在按性别进行的分析中，这种关联仅在男性中显著（OR = 1.16，95% CI = 1.03-1.31），而在女性中不显著（OR = 1.01，95% CI = 0.88-1.14）。在子样本分析中，作为高强度噪声暴露指标的听力损失与高血压风险较高相关，尤其是双侧听力损失的参与者（OR = 1.39，95% CI = 1.24-1.54）。在荟萃分析中，职业性噪声暴露与高血压之间关联的汇总OR为1.25（95% CI = 1.10-1.42）。基于职业性噪声暴露指标，横断面研究和荟萃分析确定职业性噪声暴露是高血压风险增加的一个潜在危险因素。
