焦虑症患儿血清阳性的评估
Assessment of Seropositivity in Children Suffering from Anxiety Disorders.
作者信息
Afsharpaiman Shahla, Khosravi Mohammad Hossein, Mahmoodinejad Mojtaba, Shirbazoo Shahnaz, Amirsalari Susan, Torkaman Mohammad, Radfar Shokoofeh
机构信息
Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Student Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran.
出版信息
Iran J Child Neurol. 2017 Fall;11(4):32-37.
OBJECTIVE
This study aimed to assess the seroprevalence of in children with anxiety disorders.
MATERIALS & METHODS: This cross-sectional study was conducted between Sep 2012 and May 2013 in Pediatrics Clinic of Baqiyatallah Hospital, Tehran, Iran. Children were assessed clinically. Diagnosis of patients with anxiety disorders was based on DSM-4 system, performed by child psychiatrist. Then their anti- antibodies were measured. A questionnaire was verbally administered to all individuals' parents including demographic information and questions about life style, family history, medical history, economic situation, residence, nutritional patterns and contact with animals.
RESULTS
Ninety-six male and female cases with a mean age of 8.56±2.5 and 8.42±1.9 yr underwent analysis. Anti- IgG antibody was found in one case of each group. There was no significant difference between case and control groups for serum IgG antibody (=0.14). No case individuals had Anti- IgM antibody, while it was found in one control individual. No significant difference was seen between case and control groups for IgM antibody (=0.27).
CONCLUSION
Toxoplasmosis has no direct effect on the incidence of anxiety disorders. More studies are needed with a larger volume of individuals in future.
目的
本研究旨在评估焦虑症患儿的弓形虫血清阳性率。
材料与方法
本横断面研究于2012年9月至2013年5月在伊朗德黑兰巴基耶塔拉医院儿科诊所进行。对儿童进行临床评估。焦虑症患者的诊断基于DSM - 4系统，由儿童精神科医生进行。然后检测他们的抗弓形虫抗体。向所有个体的父母口头发放一份问卷，内容包括人口统计学信息以及关于生活方式、家族史、病史、经济状况、居住地、营养模式和与动物接触情况的问题。
结果
对96例平均年龄为8.56±2.5岁的男性和平均年龄为8.42±1.9岁的女性病例进行了分析。每组各有1例检测到抗弓形虫IgG抗体。病例组和对照组血清弓形虫IgG抗体之间无显著差异（P = 0.14）。病例组个体均未检测到抗弓形虫IgM抗体，而在1例对照个体中检测到。病例组和对照组弓形虫IgM抗体之间无显著差异（P = 0.27）。
结论
弓形虫病对焦虑症的发病率没有直接影响。未来需要对更多个体进行进一步研究。
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