Scialpi Michele, D'Andrea Alfredo, Martorana Eugenio, Malaspina Corrado Maria, Aisa Maria Cristina, Napoletano Maria, Orlandi Emanuele, Rondoni Valeria, Scialpi Pietro, Pacchiarini Diamante, Palladino Diego, Dragone Michele, Di Renzo Giancarlo, Simeone Annalisa, Bianchi Giampaolo, Brunese Luca
Department of Surgical and Biomedical Sciences, Division of Radiology 2, Santa Maria della Misericordia Hospital, Perugia University, Sant' Andrea delle Fratte, Perugia, Italy.
Department of Experimental Medicine, Magrassi Lanzara, Luigi Vanvitelli, Second University of Naples, Naples, Italy.
Turk J Urol. 2017 Dec;43(4):401-409. doi: 10.5152/tud.2017.06978. Epub 2017 Dec 1.
Biparametric Magnetic Resonance Imaging (bpMRI) of the prostate combining both morphologic T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) is emerging as an alternative to multiparametric MRI (mpMRI) to detect, to localize and to guide prostatic targeted biopsy in patients with suspicious prostate cancer (PCa). BpMRI overcomes some limitations of mpMRI such as the costs, the time required to perform the study, the use of gadolinium-based contrast agents and the lack of a guidance for management of score 3 lesions equivocal for significant PCa. In our experience the optimal and similar clinical results of the bpMRI in comparison to mpMRI are essentially related to the DWI that we consider the dominant sequence for detection suspicious PCa both in transition and in peripheral zone. In clinical practice, the adoption of bpMRI standardized scoring system, indicating the likelihood to diagnose a clinically significant PCa and establishing the management of each suspicious category (from 1 to 4), could represent the rationale to simplify and to improve the current interpretation of mpMRI based on Prostate Imaging and Reporting Archiving Data System version 2 (PI-RADS v2). In this review article we report and describe the current knowledge about bpMRI in the detection of suspicious PCa and a simplified PI-RADS based on bpMRI for management of each suspicious PCa categories to facilitate the communication between radiologists and urologists.
前列腺双参数磁共振成像(bpMRI)结合形态学T2加权成像(T2WI)和扩散加权成像(DWI),正逐渐成为多参数MRI(mpMRI)的替代方法,用于检测、定位和引导对可疑前列腺癌(PCa)患者进行前列腺靶向活检。BpMRI克服了mpMRI的一些局限性,如成本、进行检查所需的时间、使用钆基造影剂以及缺乏对意义不明确的3分病变(对于显著PCa)管理的指导。根据我们的经验,与mpMRI相比,bpMRI的最佳且相似的临床结果主要与DWI相关,我们认为DWI是在移行区和外周区检测可疑PCa的主导序列。在临床实践中,采用bpMRI标准化评分系统,表明诊断临床显著PCa的可能性并确定每个可疑类别(从1到4)的管理方式,可能是简化和改进基于前列腺影像报告和数据系统第2版(PI-RADS v2)的当前mpMRI解读的基本原理。在这篇综述文章中,我们报告并描述了关于bpMRI在检测可疑PCa方面的当前知识,以及基于bpMRI的简化PI-RADS,用于管理每个可疑PCa类别,以促进放射科医生和泌尿科医生之间的沟通。