Guclu Mustafa, Faruq Agan A
Department of Gastroenterology, Istanbul Medipol University, Istanbul, Turkey.
Euroasian J Hepatogastroenterol. 2017 Jan-Jun;7(1):11-16. doi: 10.5005/jp-journals-10018-1204. Epub 2017 May 5.
To determine the correlation of infection with peripheral blood neutrophil/lymphocyte ratio (NLR) and mean platelet volume (MPV).
The NLR, MPV, platelets, leukocytes, neutrophils, and lymphocytes were calculated and the differences between groups were investigated.
A total of 199 patients were included in the study. Neutrophil/lymphocyte ratio was statistically lower in patients than in patients (1.94 ± 0.79 2.67 ± 2.35 respectively, p = 0.04). There was no significant difference between patients and patients of severe intensity in terms of MPV. However, peripheral blood lymphocytes and platelets were statistically significantly higher in patients of severe intensity (lymphocytes 2150 ± 826 2954 ± 2436 respectively, p = 0.000 and platelets 258247 ± 69494 265611 ± 113397 respectively, p = 0.02) compared with negative patients.
A moderate increase in the intensity of does not lead to a significant change in MPV as measured by hemogram; however, it gives rise to a statistically significant fall in NLR. Presence of severe intensity leads to a statistically significant increase in peripheral blood lymphocytes and platelets compared with patients. Guclu M, Agan AF. Association of Severity of Infection with Peripheral Blood Neutrophil to Lymphocyte Ratio and Mean Platelet Volume. Euroasian J Hepato-Gastroenterol 2017;7(1):11-16.
确定感染与外周血中性粒细胞/淋巴细胞比值（NLR）及平均血小板体积（MPV）之间的相关性。
计算NLR、MPV、血小板、白细胞、中性粒细胞及淋巴细胞，并研究组间差异。
本研究共纳入199例患者。患者的中性粒细胞/淋巴细胞比值在统计学上低于患者（分别为1.94±0.79和2.67±2.35，p = 0.04）。在MPV方面，患者与重度患者之间无显著差异。然而，与阴性患者相比，重度患者外周血淋巴细胞和血小板在统计学上显著更高（淋巴细胞分别为2150±826和2954±2436，p = 0.000；血小板分别为258247±69494和265611±113397，p = 0.02）。
感染强度的适度增加不会导致血常规检测的MPV出现显著变化；然而，会导致NLR在统计学上显著下降。与患者相比，重度感染会导致外周血淋巴细胞和血小板在统计学上显著增加。古鲁 M，阿甘 AF。感染严重程度与外周血中性粒细胞与淋巴细胞比值及平均血小板体积的关联。《欧亚肝脏胃肠病学杂志》2017；7(1):11 - 16。
