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与埃塞俄比亚南部 Gamo 和 Gofa 地区公立医院 2 型糖尿病成年患者血糖控制不佳相关的因素:一项病例对照研究。

Factors associated with poor glycemic control among adult patients with type 2 diabetes mellitus in Gamo and Gofa zone public hospitals, Southern Ethiopia: A case-control study.

机构信息

School of Public Health, College of Medicine and Health Science, Arba Minch University, Arba Minch, Ethiopia.

School of Medicine, College of Medicine and Health Science, Arba Minch University, Arba Minch, Ethiopia.

出版信息

PLoS One. 2023 Mar 10;18(3):e0276678. doi: 10.1371/journal.pone.0276678. eCollection 2023.

Abstract

BACKGROUND

Diabetes mellitus is a serious global public health problem that affects the whole life of people in terms of their biological, psychological, and social effects. Complications and death from diabetes occur from poorly controlled blood glucose levels. Thus, dealing with glycemic control is essential for controlling the development of devastating acute and chronic complications related to diabetes. Therefore, this study aims to assess factors associated with poor glycemic control among type2 diabetes patients in public hospitals of Gamo and Gofa zone southern, Ethiopia, 2021.

METHODS

An institution-based unmatched case-control study was employed among 312 randomly selected participants using a pre-tested, interviewer-administered, and structured questionnaire. Bivariate and multivariable logistic regression analysis was conducted to identify factors associated with poor glycemic control using IBM SPSS version 25. The strength of association was assessed by using an Adjusted odds ratio (AOR) with a 95% confidence interval (CI).

RESULT

Factors associated with poor glycemic control based on multivariable analysis were, having comorbidity (AOR = 2.35, 95% CI (1.39-3.95)), adhering to dietary recommendations (AOR = 0.31, 95% CI (089-0.51)), poor social support (AOR = 3.31, 95% CI (1.59-6.85)), physical exercise (AOR = 1.86 95% CI (1.11-3.12)), and having poly-pharmacy (AOR = 2.83, 95% CI (1.39-5.74)).

CONCLUSION AND RECOMMENDATION

This study indicated a significant association of comorbidity, physical exercise, poly-pharmacy, low social support, and adherence to dietary recommendations with poor glycemic control. We suggest that the health care providers and concerned bodies encourage patients to have regular check-ups and work on providing necessary social support.

摘要

背景

糖尿病是一个严重的全球公共卫生问题,从生物学、心理学和社会学角度影响着人们的整个生活。血糖控制不佳会导致糖尿病的急性和慢性并发症恶化,甚至导致并发症和死亡。因此,控制血糖对于控制与糖尿病相关的破坏性急性和慢性并发症的发展至关重要。因此,本研究旨在评估埃塞俄比亚甘莫和戈法地区公立 医院 2 型糖尿病患者血糖控制不佳的相关因素,研究时间为 2021 年。

方法

本研究采用基于机构的病例对照研究,在 312 名随机选择的参与者中使用经过预测试的、由访谈者管理的结构化问卷进行。采用 IBM SPSS 版本 25 进行二变量和多变量逻辑回归分析,以确定与血糖控制不佳相关的因素。采用调整后的优势比(AOR)和 95%置信区间(CI)来评估关联的强度。

结果

多变量分析显示,与血糖控制不佳相关的因素有合并症(AOR=2.35,95%CI(1.39-3.95))、遵医嘱饮食(AOR=0.31,95%CI(0.89-0.51))、社会支持差(AOR=3.31,95%CI(1.59-6.85))、体育锻炼(AOR=1.86,95%CI(1.11-3.12))和多药治疗(AOR=2.83,95%CI(1.39-5.74))。

结论和建议

本研究表明,合并症、体育锻炼、多药治疗、低社会支持和遵医嘱饮食与血糖控制不佳有显著关联。我们建议医疗保健提供者和相关机构鼓励患者定期检查,并努力提供必要的社会支持。

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