1 Division of Neurotology and Skull Base Surgery, Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, Orange, California, USA.
2 Department of Biomedical Engineering, University of California, Irvine, Orange, California, USA.
Otolaryngol Head Neck Surg. 2018 Jan;158(1):100-102. doi: 10.1177/0194599817739255. Epub 2017 Dec 5.
In this case series, we set out to describe the clinical entity of isolated, prolonged aural fullness (AF) and its relationship with migraine. Patients with isolated, persistent AF for 6 months or more were included with all possible etiologies ruled out. Migraine dietary and lifestyle changes and medical migraine prophylactic therapy were prescribed to all. Eleven patients were included (mean age, 52 years). Six (54%) patients fulfilled International Headache Society criteria for migraine with or without aura. Changes in perceived sensation of AF using the visual analog scale and quality of life questionnaires resulted in a statically significant improvement ( P < .001, 95% confidence interval [CI], 4.7 to 6.72, and P < .001, 95% CI, -5.3 to -2.7, respectively). As such, an improvement of isolated, prolonged AF with migraine lifestyle changes and prophylactic treatment may suggest an etiological association between migraine and prolonged aural fullness.
在本病例系列研究中，我们旨在描述孤立性、持续性耳闷（AF）的临床特征及其与偏头痛的关系。纳入了所有可能病因均已排除、孤立性、持续性 AF 持续 6 个月或以上的患者。所有患者均被开具偏头痛饮食和生活方式改变以及偏头痛预防性药物治疗的处方。共纳入 11 例患者（平均年龄 52 岁）。6 例（54%）患者符合国际头痛协会偏头痛伴或不伴先兆的标准。使用视觉模拟量表和生活质量问卷评估患者对 AF 感知的变化，结果显示有统计学意义的改善（P<0.001，95%置信区间 [CI]，4.7 至 6.72；P<0.001，95%CI，-5.3 至-2.7）。因此，偏头痛生活方式改变和预防性治疗可改善孤立性、持续性 AF，这可能提示偏头痛和持续性耳闷之间存在病因关联。
