Chakraborty T K, Ogilvie A L, Heading R C, Ewing D J
University Department of Medicine, Royal Infirmary, Edinburgh.
Gut. 1989 Jan;30(1):46-9. doi: 10.1136/gut.30.1.46.
Using five non-invasive tests, abnormalities of cardiovascular reflex function were found in 20 of 50 patients with gastro-oesophageal reflux. Abnormalities of pupil cycle time, an index of non-vagal parasympathetic function, were found in only a few patients, implying that the cardiovascular abnormalities observed were not part of a generalised parasympathetic defect. The findings are consistent with the hypothesis that an abnormality of vagal function may contribute to the pathogenesis of gastro-oesophageal reflux.
通过五项非侵入性测试,在50例胃食管反流患者中的20例发现了心血管反射功能异常。瞳孔周期时间异常是一种非迷走神经副交感神经功能指标,仅在少数患者中发现,这意味着观察到的心血管异常并非全身性副交感神经缺陷的一部分。这些发现与迷走神经功能异常可能导致胃食管反流发病机制的假设一致。