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大多数慢性荨麻疹患者的病情控制不佳。阿拉伯语荨麻疹控制测试的开发、验证及实际应用结果。

Chronic urticaria in most patients is poorly controlled. Results of the development, validation, and real life application of the arabic urticaria control test.

作者信息

Irani Carla, Hallit Souheil, Weller Karsten, Maurer Marcus, El Haber Carla, Salameh Pascale

机构信息

Hotel-Dieu de France, Faculty of Pharmacy, St Joseph University, Beirut, Lebanon. E-mail.

出版信息

Saudi Med J. 2017 Dec;38(12):1230-1236. doi: 10.15537/smj.2017.12.21206.

Abstract

OBJECTIVES

To translate and linguistically validate the urticaria control test (UCT) to/for Arabic speakers. No Arabic version of the UCT is available to assess disease control in patients with chronic urticaria (CU). Secondary objectives were to assess disease control in Lebanese CU patients and determine influence factors.

METHODS

This is a prospective observational study of 178 CU patients diagnosed during their first visit to a private Allergy/Immunology Clinic, Hotel Dieu de France Hospital, Beirut, Lebanon between January and December 2014.

RESULTS

Factor analysis showed that all 4 UCT items on the Arabic version converged over a solution of one factor. A high internal consistency was found with a Cronbach's alpha of 0.824. Most patients in this study had chronic spontaneous urticaria (96%), of which 19% also had inducible urticaria. The majority was less than 40 years (67.4%), with disease duration of less than 2 years (70.8%). Most patients used H1-antihistamines, but unfortunately, 34.3% used systemic glucocorticosteroids, of which 24.7% also used H1-antihistamines. The disease was poorly controlled in most patients (79.2%, UCT less than 12). Age, gender, duration, diagnosis, triggers, and/or history of atopy had no influence.

CONCLUSION

We developed the first linguistically validated Arabic UCT to improve CU management in Arabic speaking patients. We also found that disease control was poor in most CU patients, and is unaffected by age, disease duration, gender, subtype, triggers, history of atopy, and/or previous treatments.

摘要

目的

将荨麻疹控制测试(UCT)翻译成阿拉伯语并进行语言验证,以供说阿拉伯语的人群使用。目前尚无阿拉伯语版的UCT用于评估慢性荨麻疹(CU)患者的疾病控制情况。次要目标是评估黎巴嫩CU患者的疾病控制情况并确定影响因素。

方法

这是一项前瞻性观察性研究,研究对象为2014年1月至12月期间首次前往黎巴嫩贝鲁特法国主宫医院私立过敏/免疫诊所就诊的178例CU患者。

结果

因子分析显示,阿拉伯语版UCT的所有4个项目在一个因子的解决方案上收敛。发现内部一致性较高,克朗巴哈系数为0.824。本研究中的大多数患者患有慢性自发性荨麻疹(96%),其中19%也患有诱导性荨麻疹。大多数患者年龄小于40岁(67.4%),病程小于2年(70.8%)。大多数患者使用H1抗组胺药,但不幸的是,34.3%的患者使用全身性糖皮质激素,其中24.7%的患者也使用H1抗组胺药。大多数患者的疾病控制不佳(79.2%,UCT小于12)。年龄、性别、病程、诊断、诱发因素和/或特应性病史均无影响。

结论

我们开发了首个经过语言验证的阿拉伯语UCT,以改善说阿拉伯语患者的CU管理。我们还发现,大多数CU患者的疾病控制不佳,且不受年龄、病程、性别、亚型、诱发因素、特应性病史和/或既往治疗的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbee/5787635/7b990b601394/SaudiMedJ-38-1230-g003.jpg

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