INSPECT-LB: Institut National de Santé Publique, Epidémiologie Clinique et Toxicologie, Beirut, Lebanon; Lebanese American University, School of medicine, Byblos, Lebanon, Beirut.
Internal Medicine and Clinical Immunology, Hotel-Dieu de France Hospital, Saint Joseph University, Beirut.
Acta Derm Venereol. 2023 Feb 14;103:adv00865. doi: 10.2340/actadv.v102.2939.
Chronic urticaria is a debilitating disease that affects health-related quality of life, but few studies have evaluated its impact on psychological wellbeing. The aim of this study was to evaluate the quality of life of patients with chronic urticaria and determine its impact on their emotional and psychological wellbeing. A cross-sectional multicentre study of a cluster of 264 Lebanese patients visiting dermatology/immunology clinics was conducted between July 2018 and June 2020. The impact of chronic urticaria on quality of life was assessed using the Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) and Dermatology Life Quality Index (DLQI), as well as its consequences on mood changes using the Patient Health Questionnaire-9 (PHQ-9) and Beirut Distress Score 22 (BDS-22) scores. A multivariable analysis of covariates was performed to determine the effect of the triggering factors of urticaria on both CU-Q2oL and PHQ-9. A moderate negative correlation was found between Urticaria Control Test and quality of life scores as well as PHQ-9 and BDS-22 (p < 0.001). Patients with the lowest Urticaria Control Test score had the highest impairment in quality of life and depression scores. In conclusion, chronic urticaria compromises patients' quality of life and emotional wellbeing. This distress is more pronounced when the disease is more severe.
慢性荨麻疹是一种使人虚弱的疾病，会影响与健康相关的生活质量，但很少有研究评估其对心理健康的影响。本研究旨在评估慢性荨麻疹患者的生活质量，并确定其对情绪和心理健康的影响。2018 年 7 月至 2020 年 6 月期间，对 264 名黎巴嫩患者进行了一项横断面多中心研究，这些患者就诊于皮肤科/免疫科诊所。使用慢性荨麻疹生活质量问卷（CU-Q2oL）和皮肤病生活质量指数（DLQI）评估慢性荨麻疹对生活质量的影响，使用患者健康问卷-9（PHQ-9）和贝鲁特痛苦评分 22（BDS-22）评估其对情绪变化的影响。进行了多变量协方差分析，以确定荨麻疹的诱发因素对 CU-Q2oL 和 PHQ-9 的影响。发现荨麻疹控制测试与生活质量评分以及 PHQ-9 和 BDS-22 之间呈中度负相关（p<0.001）。荨麻疹控制测试得分最低的患者生活质量和抑郁评分受损最严重。总之，慢性荨麻疹会损害患者的生活质量和情绪健康。当疾病更严重时，这种困扰更为明显。
