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墓地会释放药物吗?来自德国南部的案例研究。

Do cemeteries emit drugs? A case study from southern Germany.

机构信息

Institute for Geography, Johannes Gutenberg University of Mainz, Johann-Joachim-Becher-Weg 21, 55099, Mainz, Germany.

Forensisches Toxikologisches Centrum - FTC, Munich, Germany.

出版信息

Environ Sci Pollut Res Int. 2018 Feb;25(6):5393-5400. doi: 10.1007/s11356-017-0757-9. Epub 2017 Dec 6.

Abstract

The risk of earth burials for the environment and public health is a matter of controversial debate. The aim of the present study is to characterise the drainage of cemeteries with regard to the concentration of a number of pharmaceuticals and to the soil's hydrochemical properties, and to discuss these data in comparison with data obtained for surface waters located upstream of the cemeteries. Of the 12 drainage samples analysed using LC-ESI-MS/MS, seven contained carbamazepine (< 225 ng l), five contained hydrochlorothiazide, one contained metoprolol (23 ng l) and one contained traces of ibuprofen. The surface water samples contained a larger number of different drugs (8 of the 12 drugs under investigation) and higher concentrations (e.g. metropolol 2230 ng l). The NO, NH, PO and DOC concentrations and the electrical conductivity of the cemetery drainages were in several samples higher than those of the surface water samples. The NO and NH concentrations exceeded the legal contaminant limits of drinking water in only one case. The present study found that the release of drugs and nutrients from cemeteries, measured in surface water drug loads, presents a low environmental risk. However, the study is only a snapshot and long-term monitoring of cemetery drainages, including a broad range of pharmaceuticals and detailed hydrological investigations, will have to be carried out before more substantiated statements can be made.

摘要

土葬对环境和公共健康的风险是一个有争议的话题。本研究的目的是描述公墓的排水情况,包括一些药物的浓度以及土壤的水文化学特性,并将这些数据与上游地表水的数据进行比较。在使用 LC-ESI-MS/MS 分析的 12 个排水样本中,有 7 个样本中含有卡马西平(<225ng/L),5 个样本中含有氢氯噻嗪,1 个样本中含有美托洛尔(23ng/L),1 个样本中含有布洛芬痕迹。地表水样本中含有更多种类的药物(研究的 12 种药物中有 8 种)和更高的浓度(例如美托洛尔 2230ng/L)。在几个样本中,公墓排水的 NO3、NH4、PO4 和 DOC 浓度以及电导率都高于地表水样本。仅在一个样本中,NO3 和 NH4 浓度超过了饮用水的法定污染物限值。本研究发现,从地表水药物负荷中测量到的从公墓中释放的药物和养分对环境的风险较低。然而,该研究仅是一个快照,需要对公墓排水进行长期监测,包括广泛的药物和详细的水文调查,然后才能做出更有根据的陈述。

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