Kidd A H, Esrey S A, Ujfalusi M J
Department of Virology, University of the Witwatersrand, Johannesburg, South Africa.
J Med Virol. 1989 Feb;27(2):164-9. doi: 10.1002/jmv.1890270219.
Stools from 266 children in four districts of Lesotho were examined for viruses by electron microscopy (EM) over a 5-week period. Eighty one (30.5%) of the children shed coronavirus-like particles (CVLPs). Shedding was not significantly associated with diarrhea. The proportion of children shedding these particles increased with increasing age. In one district, the prevalence of CVLP shedding (67.9%) was at least twice the prevalence in any of the other three districts. This was the only district to be sampled during the first week of the study. It was shown that the proportion of children shedding CVLPs declined during each of the 5 weeks of study. The stools of six children who shed CVLPs in the early summer of 1984-85 were negative by EM 5 months later. There was no association between the shedding of pathogenic bacteria or parasites and the presence or absence of CVLPs in the stool.
在为期5周的时间里,对莱索托四个地区的266名儿童的粪便进行了电子显微镜(EM)病毒检测。81名(30.5%)儿童排出了冠状病毒样颗粒(CVLPs)。病毒排出与腹泻无显著关联。排出这些颗粒的儿童比例随年龄增长而增加。在一个地区,CVLP排出率(67.9%)至少是其他三个地区中任何一个地区的两倍。这是研究第一周唯一进行采样的地区。结果显示,在研究的5周内,排出CVLPs的儿童比例每周都在下降。1984 - 1985年夏初排出CVLPs的6名儿童的粪便在5个月后经电子显微镜检测呈阴性。粪便中病原菌或寄生虫的排出与CVLPs的存在与否之间没有关联。