Gray C M, Singer W
Max Planck Institute for Brain Research, Frankfurt am Main, Federal Republic of Germany.
Proc Natl Acad Sci U S A. 1989 Mar;86(5):1698-702. doi: 10.1073/pnas.86.5.1698.
In areas 17 and 18 of the cat visual cortex the firing probability of neurons, in response to the presentation of optimally aligned light bars within their receptive field, oscillates with a peak frequency near 40 Hz. The neuronal firing pattern is tightly correlated with the phase and amplitude of an oscillatory local field potential recorded through the same electrode. The amplitude of the local field-potential oscillations are maximal in response to stimuli that match the orientation and direction preference of the local cluster of neurons. Single and multiunit recordings from the dorsal lateral geniculate nucleus of the thalamus showed no evidence of oscillations of the neuronal firing probability in the range of 20-70 Hz. The results demonstrate that local neuronal populations in the visual cortex engage in stimulus-specific synchronous oscillations resulting from an intracortical mechanism. The oscillatory responses may provide a general mechanism by which activity patterns in spatially separate regions of the cortex are temporally coordinated.
在猫视觉皮层的17区和18区，神经元对其感受野内最佳对齐的光条呈现的反应，其放电概率以接近40Hz的峰值频率振荡。神经元放电模式与通过同一电极记录的振荡性局部场电位的相位和幅度紧密相关。局部场电位振荡的幅度在对与局部神经元簇的方向和方向偏好相匹配的刺激作出反应时最大。来自丘脑背外侧膝状核的单单位和多单位记录未显示在20 - 70Hz范围内神经元放电概率的振荡证据。结果表明，视觉皮层中的局部神经元群体参与了由皮层内机制产生的刺激特异性同步振荡。振荡反应可能提供了一种一般机制，通过该机制，皮层空间上分离区域的活动模式在时间上得到协调。
