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家兔食欲性条件反射过程中与气味相关的延髓脑电图空间模式分析

Odor-related bulbar EEG spatial pattern analysis during appetitive conditioning in rabbits.

作者信息

Di Prisco G V, Freeman W J

出版信息

Behav Neurosci. 1985 Oct;99(5):964-78. doi: 10.1037//0735-7044.99.5.964.

DOI:10.1037//0735-7044.99.5.964
PMID:3843313
Abstract

Mildly thirsty rabbits were classically conditioned by reinforcement with water to give a discriminative licking response to the presentation of odors. The jaw movement component of the licking conditioned response (JM CR) was elicited only by the reinforced odor; an increase in the relative frequency of sniffing (RR CR) occurred to both reinforced (CS+) and nonreinforced (CS-) odors. Oscillatory electroencephalographic bursts of high-frequency (40-80 Hz) potentials were recorded epidurally from the lateral olfactory bulb with 64-electrode arrays (8 X 8, 3.5 X 3.5 mm) chronically implanted. Emphasis was on comparing bursts during odor presentation with bursts preceding odor arrival on each trial. A "detection" burst was characterized as occurring immediately after odor arrival and before the sniff response. "Discrimination" bursts occurred during the RR CR and before the JM CR onset. Significant air-odor burst differences (together with sniffing) occurred through up to six sessions for both CS+ and CS- odors for "discrimination" bursts but not for "detection" bursts.

摘要

轻度口渴的兔子通过用水强化进行经典条件反射,以对气味的呈现做出辨别性舔舐反应。舔舐条件反应(JM CR)的下颌运动成分仅由强化气味引发;对强化(CS +)和非强化(CS -)气味都出现了嗅探相对频率的增加(RR CR)。使用长期植入的64电极阵列(8×8,3.5×3.5毫米)从外侧嗅球硬膜外记录高频(40 - 80赫兹)电位的振荡脑电图爆发。重点是比较每次试验中气味呈现期间的爆发与气味到达之前的爆发。“检测”爆发的特征是在气味到达后且在嗅探反应之前立即发生。“辨别”爆发发生在RR CR期间且在JM CR开始之前。对于CS +和CS -气味,“辨别”爆发在多达六个实验阶段中都出现了显著的空气 - 气味爆发差异(与嗅探一起),但“检测”爆发没有。

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