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摄入咖啡多酚可改善皮肤表面鳞屑状况并提高冷应激后皮肤温度的恢复率:一项随机对照试验

Ingestion of Coffee Polyphenols Improves a Scaly Skin Surface and the Recovery Rate of Skin Temperature after Cold Stress: A Randomized, Controlled Trial.

作者信息

Ueda Sachie, Tanahashi Masanori, Higaki Yuko, Iwata Kayoko, Sugiyama Yoshinori

机构信息

Skin Care Products Research, Kao Corporation.

Institute of Women's Health, Tokyo Women's Medical University.

出版信息

J Nutr Sci Vitaminol (Tokyo). 2017;63(5):291-297. doi: 10.3177/jnsv.63.291.

Abstract

Coffee polyphenols (CPPs) derived from coffee beans have beneficial effects on blood pressure and vascular endothelial function. In addition, CPPs suppress ultraviolet light induced erythema. However, the effects of CPPs on dry skin and cutaneous vascular function have not been clarified. We investigated the effects of CPPs on dry skin and the recovery rate (RR) of skin temperature after a cold-stress test as a measure of vascular function in subjects with visible scaliness in a double-blind, placebo-controlled, randomized study. The subjects were divided into two groups, the CPP group and the Placebo group. In the CPP group, the subjects ingested a beverage containing 297.8 mg CPPs every day for 4 wk. The degree of skin dryness was assessed quantitatively using a Visioscan to evaluate skin scaliness and smoothness. A subjective evaluation using a visual analog scale (VAS) of skin smoothness was also used. As a result, the scaliness and smoothness of cheek skin was significantly improved after 4 wk in the CPP group compared to the Placebo group. The improvements of the VAS score on 'skin smoothness' and the RR were also observed in the CPP group but the difference was not statistically significant. However, when the CPP group was divided into subgroups of high RR and low RR, the improvement of the RR was significant in the low RR subgroup. In conclusion, our results suggest that CPPs improve skin scaliness and play a role in cutaneous blood flow regulation after cold stress.

摘要

咖啡豆中的咖啡多酚(CPPs)对血压和血管内皮功能具有有益作用。此外,CPPs可抑制紫外线诱导的红斑。然而,CPPs对干性皮肤和皮肤血管功能的影响尚未阐明。在一项双盲、安慰剂对照、随机研究中,我们调查了CPPs对干性皮肤的影响以及冷应激试验后皮肤温度恢复率(RR),以此作为有明显鳞屑的受试者血管功能的一项指标。受试者被分为两组,即CPP组和安慰剂组。在CPP组中,受试者每天摄入含有297.8毫克CPPs的饮料,持续4周。使用Visioscan定量评估皮肤干燥程度,以评估皮肤鳞屑和光滑度。还使用视觉模拟量表(VAS)对皮肤光滑度进行主观评估。结果,与安慰剂组相比,CPP组在4周后脸颊皮肤的鳞屑和光滑度有显著改善。CPP组在“皮肤光滑度”的VAS评分和RR方面也有改善,但差异无统计学意义。然而,当将CPP组分为高RR和低RR亚组时,低RR亚组的RR改善显著。总之,我们的结果表明,CPPs可改善皮肤鳞屑,并在冷应激后皮肤血流调节中发挥作用。

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