Department of Gynecological Oncology, Second Clinical College of Wuhan University, Zhongnan Hospital, Wuhan, Hubei, China.
Department of General Practice and Emergency Medicine, Karnali Academy of Health Sciences, Jumla, Nepal.
BMC Psychiatry. 2017 Dec 12;17(1):397. doi: 10.1186/s12888-017-1550-5.
Anxiety and depression are usually under diagnosed among the patients with Chronic Obstructive Pulmonary Disease (COPD), which has a negative impact on patient quality of life through restriction of activities, loss of independence, and decreased social functioning. The purpose of this study was to describe the levels and characteristics of anxiety and depression in patients with COPD in Nepal as compared to the general population.
A hospital-based observational comparative analytical study was conducted in the United Mission Hospital, Tansen and the Okhaldhunga Community Hospital, Okhaldhunga, Nepal from June 1st 2015 to April 15th 2016. A convenience sample of two groups of participants were recruited: patients with COPD (study group) and visitors to the facility (comparison group). Anxiety and depression were measured with the Beck Anxiety and Depression Inventory Scale.
A total of 198 individuals participated in the study; 93 with COPD and 105 from the general population. The mean age of the respondents was 58.24 ± 12.04 (40-82) years. The mean scores for anxiety and depression in COPD group were 23.76± 9.51 and 27.72± 9.37 respectively, while in comparison group, the mean score for anxiety was 8.01± 6.83 and depression was 11.60 ± 8.42. Both anxiety and depression scores were statistically significant between the groups with p value <0.001.
Anxiety and depression were almost three times more common in COPD patients compared to the participants from the general population. Early assessment and multi-model treatment of anxiety and depression should be part of management in COPD.
在慢性阻塞性肺疾病（COPD）患者中，焦虑和抑郁通常诊断不足，这会通过限制活动、丧失独立性和降低社交功能对患者的生活质量产生负面影响。本研究的目的是描述尼泊尔 COPD 患者的焦虑和抑郁水平和特征，并将其与一般人群进行比较。
这是一项在尼泊尔坦森的联合传教医院和奥克拉亨达的奥克拉亨达社区医院进行的基于医院的观察性比较分析研究。于 2015 年 6 月 1 日至 2016 年 4 月 15 日期间招募了两组方便样本的参与者：COPD 患者（研究组）和医院访客（对照组）。使用贝克焦虑和抑郁量表测量焦虑和抑郁。
共有 198 人参与了研究，其中 93 人患有 COPD，105 人来自普通人群。受访者的平均年龄为 58.24±12.04 岁（40-82 岁）。COPD 组的焦虑和抑郁平均得分为 23.76±9.51 和 27.72±9.37，而对照组的焦虑平均得分为 8.01±6.83，抑郁平均得分为 11.60±8.42。两组之间的焦虑和抑郁评分均具有统计学意义（p 值均<0.001）。
与一般人群相比，COPD 患者的焦虑和抑郁发生率高了近三倍。在 COPD 患者中，早期评估和多模式治疗焦虑和抑郁应成为管理的一部分。
