Buckland-Wright J C, Clarke G S, Walker S R
Anatomy Department, United Medical and Dental School of Guy's Hospital, London Bridge.
Ann Rheum Dis. 1989 Jan;48(1):25-9. doi: 10.1136/ard.48.1.25.
Microfocal radiography has been used to evaluate the relation between erosion number and erosion area in the hands and wrists of 51 patients with early to moderately advanced rheumatoid arthritis. The hands of these patients showed different patterns of erosion progression, in terms of the relation between changes in number and area, and included those showing a decrease in one or both of the erosion parameters. The mean number of erosions in the group increased between the first and second visits. By the third visit (a mean of 48 months from the onset of symptoms) the mean number of erosions in the wrist and hand of the group had approached a constant value of 75 erosions. Over the same period the mean erosion area of the group continued to increase. Measurement of changes in erosion area is a more sensitive indicator of erosion progression than erosion number, both within the group and in individual patients.
微焦点X线摄影术已被用于评估51例早期至中度类风湿性关节炎患者手部和腕部的侵蚀数量与侵蚀面积之间的关系。这些患者的手部在侵蚀数量和面积变化的关系方面呈现出不同的侵蚀进展模式，包括那些侵蚀参数一项或两项均减少的情况。该组患者的平均侵蚀数量在首次和第二次就诊之间有所增加。到第三次就诊时（症状出现后平均48个月），该组患者腕部和手部的平均侵蚀数量已接近75处的恒定值。在同一时期，该组患者的平均侵蚀面积持续增加。无论是在组内还是个体患者中，侵蚀面积变化的测量都是比侵蚀数量更敏感的侵蚀进展指标。
