Asmah Richard H, Blankson Harriet N A, Seanefu Kekeli A, Obeng-Nkrumah Noah, Awuah-Mensah Georgina, Cham Momodou, Ayeh-Kumi Patrick F
Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, College of Health Sciences, University of Ghana, Accra, Ghana.
Comboni Catholic Hospital, Sogakope, Ghana.
BMC Womens Health. 2017 Dec 13;17(1):130. doi: 10.1186/s12905-017-0489-5.
Trichomonas vaginalis (TV) infection is the most prevalent non-viral sexually transmitted pathogen worldwide. Among pregnant women, the infection may cause adverse birth outcomes such as premature rupture of membranes and premature labour. In view of the paucity of information relating to TV among Ghanaian pregnant women, this study investigated its prevalence and associated co-infections among pregnant women.
High vaginal swabs were obtained from 99 pregnant women using sterile cotton swab sticks. Wet preparation, Grams staining, culturing, coagulase and sensitivity testing were carried out to determine the presence of TV and associated microorganisms.
The prevalence of TV among the pregnant women was found to be 20.2% (n = 20). Concurring with Trichomoniasis, 75% (n = 15) of participants had other infections such as Candida with prevalence of 53% (n = 8), Proteus infection - 20% (n = 3), Streptococcus infection - 13% (n = 2) and other GNRs and Gonococci having 7% each (n = 1). Moreover, there was 86.9% (n = 86) prevalence of Staphylococcus spp. among study participants. There was statistically significant correlation between TV and Gonococci infection at a correlation co-efficient of 0.107 (P < 0.05) as well as significant correlation between TV and Proteus spp. at a correlation co-efficient of 0.189 (P < 0.05). TV infection was high (60%) among the most sexually active age group (19 to 29 yrs).
There was 20.2% prevalence of TV among the pregnant women presenting at the hospitals, with Gonococci and Proteus infections being statistically significant associated infections.
阴道毛滴虫（TV）感染是全球最常见的非病毒性性传播病原体。在孕妇中，该感染可能导致不良分娩结局，如胎膜早破和早产。鉴于加纳孕妇中与TV相关的信息匮乏，本研究调查了孕妇中TV的患病率及其相关合并感染情况。
使用无菌棉签从99名孕妇中获取高阴道拭子。进行湿片制备、革兰氏染色、培养、凝固酶和敏感性测试，以确定TV及相关微生物的存在。
发现孕妇中TV的患病率为20.2%（n = 20）。与滴虫病同时存在的是，75%（n = 15）的参与者有其他感染，如念珠菌感染患病率为53%（n = 8），变形杆菌感染 - 20%（n = 3），链球菌感染 - 13%（n = 2），其他革兰氏阴性菌和淋球菌各占7%（n = 1）。此外，研究参与者中葡萄球菌属的患病率为86.9%（n = 86）。TV与淋球菌感染之间存在统计学显著相关性，相关系数为0.107（P < 0.05），TV与变形杆菌属之间也存在显著相关性，相关系数为0.189（P < 0.05）。在性活动最活跃的年龄组（19至29岁）中，TV感染率很高（60%）。
在到医院就诊的孕妇中，TV的患病率为20.2%，淋球菌和变形杆菌感染是具有统计学显著意义的相关感染。
