口腔黏膜扁平苔藓和白斑中朗格汉斯细胞的定量评估。

A quantitative assessment of Langerhans cells in oral mucosal lichen planus and leukoplakia.

作者信息

Rich A M, Reade P C

机构信息

Department of Dental Medicine and Surgery, University of Melbourne, Faculty of Dental Science, Victoria, Australia.

出版信息

Br J Dermatol. 1989 Feb;120(2):223-8. doi: 10.1111/j.1365-2133.1989.tb07786.x.

DOI:10.1111/j.1365-2133.1989.tb07786.x

PMID:2923795

Abstract

Quantitative analysis of Langerhans cells stained with OKT6 in the epithelium of 42 patients with oral mucosal lichen planus and 14 patients with oral mucosal leukoplakia showed significantly greater numbers of Langerhans cells in lichen planus. This may reflect the role of Langerhans cells in the pathogenesis of this condition and their identification could help in distinguishing lichen planus from leukoplakia.

摘要

对42例口腔黏膜扁平苔藓患者和14例口腔黏膜白斑患者上皮组织中用OKT6染色的朗格汉斯细胞进行定量分析，结果显示扁平苔藓中的朗格汉斯细胞数量明显更多。这可能反映了朗格汉斯细胞在该病发病机制中的作用，对其进行识别有助于将扁平苔藓与白斑区分开来。