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食管癌——108例根治性放疗病例回顾

Carcinoma of the oesophagus--a review of 108 cases treated by radical radiotherapy.

作者信息

Slevin N J, Stout R

机构信息

Department of Radiotherapy and Oncology, Christie Hospital, Manchester, UK.

出版信息

Clin Radiol. 1989 Mar;40(2):200-3. doi: 10.1016/s0009-9260(89)80097-2.

Abstract

A retrospective survey was made of 108 patients accepted for radical radiotherapy over a 10-year period. The crude 5-year survival was 8.3% (9 of 108). Patients aged 65 years and over fared significantly better than patients aged less than 65 years (P = 0.04). Long-term survival was more likely with the following features: females, good general condition, tumour in the upper third of oesophagus and no more than 8 cm in length. The 5-year survival for upper third cases was 15.6% (7 of 45) so that for this site radiotherapy can reasonably be considered the treatment of choice. Hypothyroidism developed in three of the seven upper third long-term survivors.

摘要

对10年间接受根治性放疗的108例患者进行了回顾性调查。5年粗生存率为8.3%(108例中的9例)。65岁及以上患者的预后明显好于65岁以下患者(P = 0.04)。具备以下特征者更有可能长期存活:女性、一般状况良好、肿瘤位于食管上三分之一且长度不超过8 cm。食管上三分之一病例的5年生存率为15.6%(45例中的7例),因此对于该部位,放疗可合理地被视为首选治疗方法。7例食管上三分之一长期存活者中有3例发生了甲状腺功能减退。

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