Bryant G, Wolfe J
School of Physics, University of New South Wales, Kensington, Australia.
Eur Biophys J. 1989;16(6):369-74. doi: 10.1007/BF00257886.
Large repulsive forces measured between membranes of lamellar lipid phases at low hydration are attributed to hydration interactions which vary widely among lipid species. We include this interaction in a model of lamellar phases of two membrane components (two lipids or lipid and protein). The surface polarization of a mixture is taken as a linear combination of those of the components. The model predicts phase separation at low hydration. This may have important consequences for living cells which are dehydrated either by the osmotic effects of tissue freezing, or by desiccation in unsaturated atmospheres.
在低水合作用下,层状脂质相膜之间测得的较大排斥力归因于水合相互作用,这种相互作用在不同脂质种类之间差异很大。我们将这种相互作用纳入了由两种膜成分(两种脂质或脂质与蛋白质)组成的层状相模型中。混合物的表面极化被视为各成分表面极化的线性组合。该模型预测在低水合作用下会发生相分离。这可能对活细胞产生重要影响,活细胞可能因组织冷冻的渗透作用或在不饱和大气中的干燥作用而脱水。