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1
Dementia prevalence, care arrangement, and access to care in Lebanon: A pilot study.黎巴嫩的痴呆症患病率、护理安排和护理获取情况:一项试点研究。
Alzheimers Dement. 2017 Dec;13(12):1317-1326. doi: 10.1016/j.jalz.2017.04.007. Epub 2017 Jun 2.
2
A Comparison of the Prevalence of Dementia in the United States in 2000 and 2012.2000年与2012年美国痴呆症患病率比较
JAMA Intern Med. 2017 Jan 1;177(1):51-58. doi: 10.1001/jamainternmed.2016.6807.
3
Effectiveness of a 6-year multidomain vascular care intervention to prevent dementia (preDIVA): a cluster-randomised controlled trial.6 年多领域血管护理干预预防痴呆的效果(preDIVA):一项群组随机对照试验。
Lancet. 2016 Aug 20;388(10046):797-805. doi: 10.1016/S0140-6736(16)30950-3. Epub 2016 Jul 26.
4
Profiling of Alzheimer's disease patients in Puerto Rico: A comparison of two distinct socioeconomic areas.波多黎各阿尔茨海默病患者的概况分析:两个不同社会经济区域的比较。
SAGE Open Med. 2016 Jan 29;4:2050312115627826. doi: 10.1177/2050312115627826. eCollection 2016.
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Hypertension and Its Role in Cognitive Function: Current Evidence and Challenges for the Future.高血压及其在认知功能中的作用:当前证据与未来挑战
Am J Hypertens. 2016 Feb;29(2):149-57. doi: 10.1093/ajh/hpv180. Epub 2015 Nov 11.
6
Hypertension in patients with Alzheimer's disease--prevalence, characteristics, and impact on clinical outcome. Experience of one neurology center in Poland.阿尔茨海默病患者的高血压——患病率、特征及其对临床结局的影响。波兰一家神经科中心的经验。
J Am Soc Hypertens. 2015 Sep;9(9):711-24. doi: 10.1016/j.jash.2015.07.002. Epub 2015 Jul 9.
7
A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial.一项针对高危老年人的饮食、运动、认知训练和血管风险监测的 2 年多领域干预措施,以预防认知能力下降(FINGER):一项随机对照试验。
Lancet. 2015 Jun 6;385(9984):2255-63. doi: 10.1016/S0140-6736(15)60461-5. Epub 2015 Mar 12.
8
Target risk factors for dementia prevention: a systematic review and Delphi consensus study on the evidence from observational studies.预防痴呆症的目标风险因素:基于观察性研究证据的系统评价与德尔菲共识研究
Int J Geriatr Psychiatry. 2015 Mar;30(3):234-46. doi: 10.1002/gps.4245. Epub 2014 Dec 12.
9
Physical activity, weight status, diabetes and dementia: a 34-year follow-up of the population study of women in Gothenburg.体力活动、体重状况、糖尿病与痴呆:哥德堡女性人群研究 34 年随访。
Neuroepidemiology. 2014;42(4):252-9. doi: 10.1159/000362201. Epub 2014 Jun 7.
10
Validation of the 10/66 Dementia Research Group diagnostic assessment for dementia in Arabic: a study in Lebanon.10/66痴呆研究小组痴呆诊断评估在阿拉伯语中的效度验证:黎巴嫩的一项研究。
J Geriatr Psychiatry Neurol. 2014 Dec;27(4):282-90. doi: 10.1177/0891988714532019. Epub 2014 Apr 25.

与痴呆症相关的社会人口统计学和心血管疾病风险因素:黎巴嫩一项横断面研究的结果。

Socio-demographic and cardiovascular disease risk factors associated with dementia: Results of a cross-sectional study from Lebanon.

作者信息

Chaaya Monique, Phung Kieu, Atweh Samir, El Asmar Khalil, Karam Georges, Khoury Rose Mary, Ghandour Lilian, Ghusn Husam, Assaad Sarah, Prince Martin, Waldemar Gunhild

机构信息

Department of Epidemiology and Population Health, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon.

Department of Neurology, Danish Dementia Research Center, The Neuroscience Center, University of Copenhagen, Copenhagen, Denmark.

出版信息

Prev Med Rep. 2017 Nov 24;9:1-5. doi: 10.1016/j.pmedr.2017.11.006. eCollection 2018 Mar.

DOI:10.1016/j.pmedr.2017.11.006
PMID:29255666
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5723378/
Abstract

Little evidence from the Arab region is available on dementia and its associated risk factors. This study is the first in Lebanon to examine the association between community older adults' socio-demographics and cardiovascular disease risk factors (CVDRF) and dementia in the aim of closing the knowledge gap. A cross-sectional household survey was conducted in 2013 in Beirut and two districts of Mount Lebanon with 502 older adults (65 years and above) and their informants. Data was collected on CVDRF and socio-demographics using structured questionnaires and dementia was assessed using the 10/66 Dementia Research Group validated tools. Multivariable analysis was done using a generalized estimating equation to account for cluster effect. Being older and perceiving personal income as insufficient significantly increased the odds of dementia [OR = 4.00 (95%CI = 1.46, 10.95); OR = 7.07 (1.84, 27.03); OR = 3.90 (1.58, 9.60)]. Having uncontrolled hypertension (versus no hypertension) was the only significant CVDRF that increased the odds of dementia [OR = 6.35 (1.60, 25.10)]. Interventions targeting uncontrolled hypertension that aim to increase awareness about proper management of this chronic condition would contribute to the needed preventive efforts against CVDRFs in response to dementia risk. Further research on the association between income sufficiency - one indicator of low socio-economic status - and dementia is warranted.

摘要

阿拉伯地区关于痴呆症及其相关风险因素的证据很少。本研究是黎巴嫩首次针对社区老年人的社会人口统计学特征与心血管疾病风险因素(CVDRF)和痴呆症之间的关联进行的研究,旨在填补知识空白。2013年在贝鲁特和黎巴嫩山的两个地区对502名老年人(65岁及以上)及其 informant 进行了横断面家庭调查。使用结构化问卷收集了关于CVDRF和社会人口统计学的数据,并使用10/66痴呆症研究小组验证的工具对痴呆症进行了评估。使用广义估计方程进行多变量分析以考虑聚类效应。年龄较大以及认为个人收入不足会显著增加患痴呆症的几率[比值比(OR)=4.00(95%置信区间(CI)=1.46,10.95);OR=7.07(1.84,27.03);OR=3.90(1.58,9.60)]。患有未控制的高血压(与无高血压相比)是唯一显著增加患痴呆症几率的CVDRF[OR=6.35(1.60,25.10)]。针对未控制的高血压进行干预,旨在提高对这种慢性病适当管理的认识,这将有助于应对痴呆症风险,开展针对CVDRF所需的预防工作。有必要对收入充足(社会经济地位低的一个指标)与痴呆症之间的关联进行进一步研究。