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结核病:常见问题解答。

Tuberculosis: Just the FAQs.

机构信息

Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.

Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA

出版信息

mBio. 2017 Dec 19;8(6):e01910-17. doi: 10.1128/mBio.01910-17.

DOI:10.1128/mBio.01910-17
PMID:29259086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5736911/
Abstract

Tuberculosis is responsible for more deaths worldwide than any other infectious disease. For anyone looking to learn more about this persistent public health threat, this conversational "frequently asked questions" style review addresses a breadth of questions. It offers a brief, somewhat opinionated, review of what is and is not known, particularly in light of how findings in the lab do or do not help inform the understanding of human tuberculosis.

摘要

结核病是全球导致死亡人数超过其他任何传染病的疾病。对于任何想要了解更多关于这一持续存在的公共卫生威胁的人来说,这本以对话形式呈现的“常见问题解答”风格的评论文章涵盖了广泛的问题。它简要地、略带个人观点地回顾了已知和未知的内容,特别是鉴于实验室的发现是否有助于或无助于理解人类结核病。

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Tuberculosis: Just the FAQs.结核病:常见问题解答。
mBio. 2017 Dec 19;8(6):e01910-17. doi: 10.1128/mBio.01910-17.
2
Tuberculosis controlling, from China's perspective.从中国视角看结核病防控
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Can Commun Dis Rep. 1996 Apr;22 Suppl 1:i-iv, 1-50, i-iv, 1-55.
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No man is an island: reducing diagnostic delays in undocumented foreign-born persons is needed to decrease the risk of tuberculosis transmission.没有人是一座孤岛:减少对身份不明的外国出生者的诊断延误对于降低结核病传播风险至关重要。
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Can routine genetic testing help to end TB transmission?常规基因检测有助于终结结核病传播吗?
Thorax. 2016 Aug;71(8):681-2. doi: 10.1136/thoraxjnl-2016-208554.
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Household contact investigation to improve tuberculosis control.开展家庭接触者调查以改善结核病防控。
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Dual delivery of antigens shows promise.双重抗原递呈显示出良好的前景。
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Integrated bioinformatic analyses investigate macrophage-M1-related biomarkers and tuberculosis therapeutic drugs.综合生物信息学分析研究巨噬细胞M1相关生物标志物和结核病治疗药物。
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本文引用的文献

1
Targeting Phenotypically Tolerant Mycobacterium tuberculosis.针对表型耐受的结核分枝杆菌。
Microbiol Spectr. 2017 Jan;5(1). doi: 10.1128/microbiolspec.TBTB2-0031-2016.
2
Antibodies to Mycobacterium tuberculosis.结核分枝杆菌抗体。
N Engl J Med. 2017 Jan 19;376(3):283-285. doi: 10.1056/NEJMcibr1613268.
3
Transmission of Extensively Drug-Resistant Tuberculosis in South Africa.南非广泛耐药结核病的传播
N Engl J Med. 2017 Jan 19;376(3):243-253. doi: 10.1056/NEJMoa1604544.
4
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015.1980 - 2015年全球、区域和国家249种死因的预期寿命、全死因死亡率和死因别死亡率:全球疾病负担研究2015的系统分析
Lancet. 2016 Oct 8;388(10053):1459-1544. doi: 10.1016/S0140-6736(16)31012-1.
5
A Functional Role for Antibodies in Tuberculosis.抗体在结核病中的功能作用
Cell. 2016 Oct 6;167(2):433-443.e14. doi: 10.1016/j.cell.2016.08.072. Epub 2016 Sep 22.
6
Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure.肺结核治愈后正电子发射断层扫描病变活动及结核分枝杆菌mRNA持续存在
Nat Med. 2016 Oct;22(10):1094-1100. doi: 10.1038/nm.4177. Epub 2016 Sep 5.
7
Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[F]fluoro-D-glucose positron emission and computed tomography.利用2-脱氧-2-[F]氟-D-葡萄糖正电子发射断层扫描和计算机断层扫描对进展性HIV相关结核病进行特征分析。
Nat Med. 2016 Oct;22(10):1090-1093. doi: 10.1038/nm.4161. Epub 2016 Sep 5.
8
Detection and Quantification of Differentially Culturable Tubercle Bacteria in Sputum from Patients with Tuberculosis.肺结核患者痰液中可培养差异结核分枝杆菌的检测与定量分析
Am J Respir Crit Care Med. 2016 Dec 15;194(12):1532-1540. doi: 10.1164/rccm.201604-0769OC.
9
PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis.正电子发射断层扫描-计算机断层扫描(PET CT)可识别携带潜伏性结核分枝杆菌的食蟹猴的再激活风险。
PLoS Pathog. 2016 Jul 5;12(7):e1005739. doi: 10.1371/journal.ppat.1005739. eCollection 2016 Jul.
10
High Persister Mutants in Mycobacterium tuberculosis.结核分枝杆菌中的高持久性突变体
PLoS One. 2016 May 13;11(5):e0155127. doi: 10.1371/journal.pone.0155127. eCollection 2016.