Davies J P, O'Connor D O, Burke D W, Greer J A, Harris W H
Orthopaedic Biomechanics Laboratory, Massachusetts General Hospital, Boston 02114.
J Arthroplasty. 1989;4(1):15-20. doi: 10.1016/s0883-5403(89)80048-8.
Simplex P bone cement was spun for 30, 60, and 120 seconds in three different centrifugation systems (I.E.C. HN-S II, I.E.C. clinical, and Johnson & Johnson) to determine whether differences among the three systems also produce differences in the improvement of the fatigue strength of the cement. The fatigue properties of the cement after centrifugation were also assessed when it was mixed with monomer that had been chilled to 0 degrees C. There were important and statistically significant differences in the fatigue life of Simplex P spun for the same duration in the different centrifuges. Simplex P prepared as recommended by the manufacturer had an average fatigue life of 15,143 cycles in the test system used. Optimum centrifugation among the techniques studied increased the fatigue life nearly fivefold, to the range of 71,000 cycles. Taking into account both the fatigue strength and the viscosity of the cement, the optimum centrifugation system for improving the fatigue life of Simplex P bone cement is the Miller cartridge containing two packs of cement spun in the IEC-HN-S II centrifuge. The authors recommend 30 seconds of centrifugation if the monomer is not chilled prior to mixing and 60 seconds if the monomer is chilled.
在三种不同的离心系统（I.E.C. HN-S II、I.E.C.临床型和强生公司的系统）中，对单纯形P骨水泥分别进行30秒、60秒和120秒的离心，以确定这三种系统之间的差异是否也会导致水泥疲劳强度改善方面的差异。当水泥与冷却至0摄氏度的单体混合时，还评估了离心后水泥的疲劳性能。在不同离心机中以相同时间离心的单纯形P骨水泥的疲劳寿命存在重要且具有统计学意义的差异。按照制造商的建议制备的单纯形P骨水泥在所用测试系统中的平均疲劳寿命为15143次循环。在所研究的技术中，最佳离心操作可使疲劳寿命增加近五倍，达到71000次循环的范围。综合考虑水泥的疲劳强度和粘度，用于提高单纯形P骨水泥疲劳寿命的最佳离心系统是在IEC-HN-S II离心机中离心装有两包水泥的米勒药筒。作者建议，如果单体在混合前未冷却，则离心30秒；如果单体已冷却，则离心60秒。
