卢戈氏染色内镜检查在头颈部癌随访中的应用
Lugol Chromoscopy in the Follow-up of Head and Neck Carcinoma.
作者信息
Simões Cesar Augusto, Durazzo Marcelo Doria, de Aquino Xavier Flávia Caló, Gallottini Marina Helena Cury, Lourenço Sílvia Vanessa, Pinto Júnior Décio Dos Santos, Magacho de Andrade Natália Martins, Miazaki Aline Paterno, Dedivitis Rogério Aparecido, Cernea Cláudio Roberto
机构信息
Department of Head and Neck Surgery, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
Department of Stomatology, University of São Paulo Dental School, São Paulo, Brazil.
出版信息
Ann Maxillofac Surg. 2017 Jul-Dec;7(2):188-193. doi: 10.4103/ams.ams_95_17.
INTRODUCTION
Lugol is helpful in identifying early second primary tumors (SPTs) during oroscopy and pharyngoscopy, but this technique has not been assessed during follow-up visits with these patients.
AIM
The aim of this study is to describe the use of Lugol (a low-cost method) to diagnose SPTs in the oral cavity and oropharynx.
METHODS
Patients treated for squamous cell carcinoma of the head and neck were randomly assigned to two groups. Group A was examined with routine oroscopy and pharyngoscopy without Lugol, and Group B was examined with routine oroscopy and pharyngoscopy without stain and with Lugol. A total of 211 patients were included during 4 years.
RESULTS
Six oral and oropharynx carcinomas were detected in Group A. Eighteen oral and oropharynx carcinomas were detected in Group B, twelve of which were not seen without chromoscopy but were detected with Lugol.
CONCLUSION
Lugol increases the detection of malignant lesions compared to routine examination alone.
引言
卢戈氏碘液有助于在喉镜检查和咽镜检查期间识别早期第二原发性肿瘤（SPT），但尚未对这些患者随访期间的该技术进行评估。
目的
本研究的目的是描述使用卢戈氏碘液（一种低成本方法）诊断口腔和口咽的第二原发性肿瘤。
方法
接受头颈部鳞状细胞癌治疗的患者被随机分为两组。A组采用无卢戈氏碘液的常规喉镜检查和咽镜检查，B组采用无染色剂的常规喉镜检查和咽镜检查以及卢戈氏碘液检查。4年间共纳入211例患者。
结果
A组检测到6例口腔和口咽癌。B组检测到18例口腔和口咽癌，其中12例在未进行染色检查时未被发现，但经卢戈氏碘液检测到。
结论
与单纯常规检查相比，卢戈氏碘液增加了恶性病变的检出率。
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