Ghassemi Fariba, Mirshahi Reza, Bazvand Fatemeh, Fadakar Kaveh, Faghihi Houshang, Sabour Siamak
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Retina & Vitreous Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
J Curr Ophthalmol. 2017 Jul 29;29(4):293-299. doi: 10.1016/j.joco.2017.06.004. eCollection 2017 Dec.
To provide normative data of foveal avascular zone (FAZ) and thickness.
In this cross-sectional study both eyes of each normal subject were scanned with optical coherence tomography angiography (OCTA) for foveal superficial and deep avascular zone (FAZ) and central foveal thickness (CFT) and parafoveal thickness (PFT).
Out of a total of 224 eyes of 112 volunteers with a mean age of 37.03 (12-67) years, the mean superficial FAZ area was 0.27 mm, and deep FAZ area was 0.35 mm ( < 0.001), with no difference between both eyes. Females had a larger superficial (0.32 ± 0.11 mm versus 0.23 ± 0.09 mm) and deep FAZ (0.40 ± 0.14 mm versus 0.31 ± 0.10 mm) ( < 0.001) than males. By multivariate linear regression analysis, in normal eyes, superficial FAZ area varied significantly with the gender, CFT, and deep FAZ. Deep FAZ varied with the gender and CFT.
The gender and CFT influence the size of normal superficial and deep FAZ of capillary network.
提供黄斑无血管区（FAZ）及其厚度的规范数据。
在这项横断面研究中，使用光学相干断层扫描血管造影（OCTA）对每位正常受试者的双眼进行扫描，以测量黄斑浅层和深层无血管区（FAZ）、中心凹黄斑厚度（CFT）和旁中心凹厚度（PFT）。
在112名平均年龄为37.03岁（12 - 67岁）的志愿者的224只眼中，浅层FAZ平均面积为0.27平方毫米，深层FAZ平均面积为0.35平方毫米（<0.001），双眼之间无差异。女性的浅层FAZ（0.32±0.11平方毫米对0.23±0.09平方毫米）和深层FAZ（0.40±0.14平方毫米对0.31±0.10平方毫米）均大于男性（<0.001）。通过多变量线性回归分析，在正常眼中，浅层FAZ面积随性别、CFT和深层FAZ有显著变化。深层FAZ随性别和CFT而变化。
性别和CFT影响正常毛细血管网浅层和深层FAZ的大小。
