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基于三维打印技术对犬上颌骨肿瘤切除术后骨缺损的重建

Three-Dimensional Printing-based Reconstruction of a Maxillary Bone Defect in a Dog Following Tumor Removal.

作者信息

Kim Se Eun, Shim Kyung Mi, Jang Kwangsik, Shim Jin-Hyung, Kang Seong Soo

机构信息

Biomaterial R&BD Center, Chonnam National University, Gwangju, Republic of Korea.

Department of Veterinary surgery, College of Veterinary Medicine and BK21 Plus Project Team, Chonnam National University, Gwangju, Republic of Korea.

出版信息

In Vivo. 2018 Jan-Feb;32(1):63-70. doi: 10.21873/invivo.11205.

Abstract

Three-dimensional (3D) printing has been applied extensively not only in human, but also veterinary medicine. However, the technique is still used in the clinical area for a surgical plan or education prior to surgery. Thus, we report a case of reconstruction after tumor removal surgery with the use of a 3D-printed scaffold. A 12-year-old female mixed dog had a left caudal maxillary mass. Based on computed tomography images, a defect was confirmed on the maxillary bone due to the oral mass, and a surgical plan was designed to remove the oral mass and graft the 3D printed scaffold. Customized polycaprolactone/ beta-tracalciumphosphate (PCL/β-TCP) scaffold was fabricated using the micro-extrusion-based 3D printer. In the operation, after the removal of the oral mass, the scaffold was grafted onto the defect site. At follow-up, 8 months after surgery, the result was successful without any special problems in the periodic CT scans and oral examinations. This case is believed to be the first case of reconstruction by using a 3D printed scaffold in the maxillary bone defect, and this 3D printing technique is thought to be very helpful for veterinary patients with bone defects and several other diseases.

摘要

三维(3D)打印不仅在人类医学,而且在兽医学中都得到了广泛应用。然而,该技术在临床领域仍仅用于手术计划或术前教育。因此,我们报告了一例使用3D打印支架进行肿瘤切除术后重建的病例。一只12岁的雌性混种犬左侧上颌尾部有肿物。根据计算机断层扫描图像,确认由于口腔肿物导致上颌骨出现缺损,并设计了手术方案来切除口腔肿物并植入3D打印支架。使用基于微挤压的3D打印机制作了定制的聚己内酯/β-磷酸三钙(PCL/β-TCP)支架。手术中,切除口腔肿物后,将支架植入缺损部位。在术后8个月的随访中,定期CT扫描和口腔检查结果显示成功,没有任何特殊问题。据信,该病例是上颌骨缺损使用3D打印支架进行重建的首例,并且这种3D打印技术被认为对患有骨缺损和其他几种疾病的兽医患者非常有帮助。

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本文引用的文献

1
Outcome and prognostic factors following curative-intent surgery for oral tumours in dogs: 234 cases (2004 to 2014).
J Small Anim Pract. 2017 Mar;58(3):146-153. doi: 10.1111/jsap.12624. Epub 2017 Feb 22.
3
Large Bone Vertical Augmentation Using a Three-Dimensional Printed TCP/HA Bone Graft: A Pilot Study in Dog Mandible.
Clin Implant Dent Relat Res. 2016 Dec;18(6):1183-1192. doi: 10.1111/cid.12394. Epub 2016 Feb 21.
4
Advantages and disadvantages of 3-dimensional printing in surgery: A systematic review.
Surgery. 2016 Jun;159(6):1485-1500. doi: 10.1016/j.surg.2015.12.017. Epub 2016 Jan 30.
5
3D modeling, custom implants and its future perspectives in craniofacial surgery.
Ann Maxillofac Surg. 2014 Jan;4(1):9-18. doi: 10.4103/2231-0746.133065.
6
Scaffold design for bone regeneration.
J Nanosci Nanotechnol. 2014 Jan;14(1):15-56. doi: 10.1166/jnn.2014.9127.
7
Three-dimensional printing of rhBMP-2-loaded scaffolds with long-term delivery for enhanced bone regeneration in a rabbit diaphyseal defect.
Tissue Eng Part A. 2014 Jul;20(13-14):1980-92. doi: 10.1089/ten.TEA.2013.0513. Epub 2014 Mar 21.
8
Evaluation of osteoconductive scaffolds in the canine femoral multi-defect model.
Tissue Eng Part A. 2013 Mar;19(5-6):634-48. doi: 10.1089/ten.TEA.2012.0289.
9
Concise review: personalized human bone grafts for reconstructing head and face.
Stem Cells Transl Med. 2012 Jan;1(1):64-9. doi: 10.5966/sctm.2011-0020. Epub 2011 Dec 7.
10
3D printing based on imaging data: review of medical applications.
Int J Comput Assist Radiol Surg. 2010 Jul;5(4):335-41. doi: 10.1007/s11548-010-0476-x. Epub 2010 May 15.

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